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The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Longer CAG repeat lengths in the androgen receptor gene are linked to higher testosterone levels in women with PCOS.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

Finasteride may improve prostate cancer treatment outcomes.

The T-zone on the face has more androgen receptors and produces more oil than the U-zone.

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

Women with hair loss have more androgen receptors in certain hair follicles.

Androgen receptors in the mouse brain may explain cognitive and mood changes in prostate cancer treatment.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

New patents show progress in developing drugs targeting the Wnt pathway for diseases like cancer and hair loss.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Human skin cells contain Protease Nexin-1, and male hormones can decrease its levels, potentially affecting hair growth.

Blocking testosterone speeds up wound healing in males.

Minoxidil can reduce functions related to androgen receptors.

Blocking testosterone speeds up wound healing in males.

Proscar (finasteride) blocks 5α-reductase in sea urchin ovaries and testes, suggesting potential treatment for androgen-related conditions.

Early hormones shape sex-specific differences in rat glands.

Understanding how androgens and their receptors work can lead to improved treatments for skin diseases.

Blocking androgen activity in newborn rats affects body weight and appetite-related hormones differently in males and females.

Sansevieria trifasciata Prain shows promise for treating hair loss by inhibiting androgen receptors.

Sex and stress steroids quickly change brain cell structures in the hippocampus.

Plant extracts can help prevent hair loss and promote hair growth.

PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.