research Repurposing Existing Drugs for COVID-19: An Endocrinology Perspective
Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.
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research Anti-Androgens May Protect Against Severe COVID-19 Outcomes: Results From a Prospective Cohort Study of 77 Hospitalized Men
Anti-androgens, like finasteride, dutasteride, and spironolactone, may lessen the severity of COVID-19 in men, leading to fewer ICU admissions.
research 5-Alpha-Reductase Inhibitors Are Associated With Reduced Frequency of COVID-19 Symptoms in Males With Androgenetic Alopecia
5-alpha-reductase inhibitors may reduce COVID-19 symptoms in bald males.
research Spironolactone: An Anti-Androgenic and Anti-Hypertensive Drug That May Provide Protection Against the Novel Coronavirus (SARS-CoV-2) Induced Acute Respiratory Distress Syndrome (ARDS) in COVID-19
Spironolactone might help protect against severe lung problems in COVID-19 patients.
research The Use of Mesenchymal Stromal Cells in the Treatment of Coronavirus Disease 2019
Mesenchymal stromal cells may help treat severe COVID-19, but more research is needed to confirm their effectiveness.
research Steady-State Pharmacokinetics of Oral Testosterone Undecanoate with Concomitant Inhibition of 5α-Reductase by Finasteride
Finasteride doesn't affect oral testosterone undecanoate, and high DHT levels may cause acne, prostate issues, and hair loss.
research COVID-19 and Endocrine and Metabolic Diseases: An Updated Statement from the European Society of Endocrinology
People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.
research The Impact of SARS-CoV-2 and COVID-19 on Male Reproduction and Men's Health
COVID-19 might affect male fertility, but more research is needed to understand the full impact.
research Are Sex Discordant Outcomes in COVID-19 Related to Sex Hormones?
Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.
research Alopecia and Grey Hair Are Associated with COVID-19 Severity
Having a lot of gray hair and hair loss are linked to more severe COVID-19.
research COVID-19 and Andrology: Recommendations of the French-Speaking Society of Andrology
Wait 3 months after COVID-19 before trying assisted reproduction and further research is needed on COVID-19's effects on male hormones and fertility.
research Therapeutic Hotline: Treatment of Androgenic Alopecia with Finasteride May Result in High-Grade Prostate Cancer in Patients: Fact or Fiction?
Finasteride for hair loss is safe and does not increase the risk of high-grade prostate cancer.
research Crystal Structure of Steroid Reductase SRD5A Reveals Conserved Steroid Reduction Mechanism
The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.
research Early Antiandrogen Therapy With Dutasteride Reduces Viral Shedding, Inflammatory Responses, and Time-to-Remission in Males With COVID-19: A Randomized, Double-Blind, Placebo-Controlled Interventional Trial
Dutasteride treatment in men with mild to moderate COVID-19 reduced viral shedding, inflammation, and recovery time without serious side effects.
research Alopecia in Patients with COVID-19: A Systematic Review and Meta-Analysis
Some COVID-19 patients lose hair, with the most common type linked to male hormones and possibly increasing the risk of severe illness.
research Are Sex Hormones Promising Candidates to Explain Sex Disparities in the COVID-19 Pandemic?
Sex hormones like estrogen and testosterone may affect COVID-19 severity differently in men and women, potentially influencing prevention and treatment strategies.
research Women’s Hair Loss: Pathophysiological, Diagnostic and Therapeutic Aspects
Accurate diagnosis and personalized treatment are crucial for managing women's hair loss.
research Immunoreactivity of the SARS-CoV-2 Entry Proteins ACE-2 and TMPRSS-2 in Murine Models of Hormonal Manipulation, Aging, and Cardiac Injury
Age affects how certain proteins involved in COVID-19 infection are expressed in mice, but sex hormones and heart injury do not.
research Hormone Replacement Therapy and COVID-19 Outcomes in Solid Organ Transplant Recipients Compared With the General Population
Hormone replacement therapy may lower the risk of severe COVID-19 outcomes in non-immunosuppressed people and male organ transplant recipients.
research Testosterone in COVID-19: An Adversary Bane or Comrade Boon
Testosterone's effects on COVID-19 are unclear and need more research.
research Post-SARS-CoV-2 Acute Telogen Effluvium: An Expected Complication
Many COVID-19 patients experience temporary hair loss after infection, not linked to infection severity or treatment.
research Insights Into the Scenario of SARS-CoV-2 Infection in Male Reproductive Toxicity
COVID-19 may harm male reproductive health and lower testosterone levels, potentially affecting fertility and causing erectile dysfunction. More research is needed.
research Recent Discoveries and Developments of Androgen Receptor-Based Therapy for Prostate Cancer
New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.
research New Insights Into Molecular Signaling Pathways And Current Advancements In Prostate Cancer Diagnostics And Therapeutics
New drugs and therapies targeting specific pathways show promise in treating advanced prostate cancer.
research Prostate Cancer Update: 2007
2007 research improved understanding of prostate cancer risk, diagnosis, and treatment, but also showed the need for personalized treatment and further study on certain therapies' risks.
research This Month in Adult Urology
The document highlights recent findings and treatments in urology, including prostate cancer diagnostics, urinary incontinence, and new therapies.
research Prostate Cancer Update: 2007
In 2007, prostate cancer research improved understanding of risk, diagnosis, and treatment, but also showed heart risks with certain therapies and the need for personalized care.
research From Gene to Therapy in Spinal and Bulbar Muscular Atrophy: Are We There Yet?
Effective treatments for spinal and bulbar muscular atrophy are not yet available; more research is needed.
research COVID-19: Understanding Inter-Individual Variability and Implications for Precision Medicine
The conclusion is that individual differences in COVID-19 severity are influenced by factors like age, sex, race, and genetics, which are important for personalized medicine.
research Side Effects of Androgen Deprivation Therapy: Monitoring and Minimizing Toxicity
Androgen deprivation therapy for prostate cancer can cause sexual, physical, and psychological side effects, and doctors should manage these carefully.