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Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.

Androgen self-administration might be controlled by membrane receptors, not nuclear ones.

Stauntonia hexaphylla extract can help treat hair loss by blocking certain hormones.

Finasteride in male rats causes liver and metabolic issues in their offspring.

Germacrone in Curcuma aeruginosa extract degrades at high temperatures but is stable in certain solutions and unaffected by pH levels.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.

Melanoma risk tools need improvement, certain gene mutations cause skin diseases and could be treated by targeting those mutations, skin wrinkling may relate to lung aging due to genetic factors, and oxidative stress affects hair loss but can be reduced in low oxygen.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

Hormonal treatments are effective for severe or persistent acne and should be used with other acne therapies, considering potential side effects.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Effective treatments for spinal and bulbar muscular atrophy are not yet available; more research is needed.

Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.

The document concludes that hair biology is complex and there are still unanswered questions about hair loss and follicle changes.

Testosterone can both promote hair growth and cause baldness by affecting hair growth signals.

Finasteride safely treats enlarged prostate and male-pattern baldness.

Citrullus colocynthis and Citrullus lanatus have potential health benefits but may also cause reproductive toxicity.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Clinicians should use social and prescription data to track trends in performance-enhancing drug use.

Exosomes from stem cells help hair regrowth by activating a specific signaling pathway.

Effective PCOS treatments require targeting specific signaling pathways.

Environmental, chemical, mechanical, and personal health factors can all damage hair and contribute to hair loss or changes in hair quality.

A yeast-based test can detect the steroid methyltestosterone in urine longer than traditional methods.

New drug shows promise for better hair growth in baldness treatment.