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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.

Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

The study found that certain microRNAs are higher in the cells and lower in the fluid of women with a specific type of polycystic ovary syndrome, and one microRNA could potentially help diagnose the condition.

DHT, a testosterone byproduct, causes male pattern baldness.

The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.

Hormonal treatments are effective for severe or persistent acne and should be used with other acne therapies, considering potential side effects.

Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.

Non-classic congenital adrenal hyperplasia is a common disorder causing symptoms like acne and infertility, and it's managed based on symptoms, not just test results. Treatment can improve fertility and reduce miscarriage risk.

Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.

Steroidogenic isoenzymes may help improve treatments for common hair loss.

Nonclassic congenital adrenal hyperplasia is a genetic disorder causing hormone imbalances, affecting fertility and requiring personalized treatment.

Flutamide combined with an LHRH agonist effectively inhibits prostate growth, suggesting it could treat prostate cancer.

Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.

Hair loss involves immune responses, inflammation, and disrupted signaling pathways.

The study found that women with hyperandrogenic PCOS have higher levels of AKT1 and AKT2 proteins in their cells, which may lead to cell dysfunction.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.