2 citations,
December 2022 in “Pharmaceutics” The enzyme pyruvate kinase M2 helps hair regrowth and could be a potential treatment for hair loss.
578 citations,
April 1993 in “Cell” TGFα gene mutation in mice causes abnormal skin, wavy hair, curly whiskers, and sometimes eye inflammation.
194 citations,
November 2006 in “Science” A genetic mutation in the LIPH gene causes hair loss and growth defects.
70 citations,
February 2018 in “Seminars in Arthritis and Rheumatism” Belimumab reduces disease activity, steroid use, and flares in lupus patients.
47 citations,
September 2022 in “European Heart Journal” Women may need different blood pressure guidelines than men for heart disease prevention.
32 citations,
February 2016 in “The American journal of dermatopathology/American journal of dermatopathology” Extramammary Paget disease can spread deeply into tissues, reaching up to 3.6 mm.
28 citations,
April 2014 in “Hormones” Higher androstenedione levels in women with PCOS are linked to more severe symptoms.
16 citations,
January 2012 in “European Journal of Endocrinology” The study suggests certain ACE gene variations are more common in women with PCOS and may be linked to increased insulin resistance.
15 citations,
October 2011 in “Gynecological Endocrinology” Obesity changes androgen levels in women with PCOS, leading to higher testosterone relative to androstenedione.
12 citations,
July 2019 in “Acta Neurologica Belgica” Levodopa for Parkinson's disease might be linked to skin issues like melanoma, but it's unclear if the drug or the disease causes them.
8 citations,
April 2020 in “Journal of The American Academy of Dermatology” Oral minoxidil is a reasonably safe alternative for patients allergic to the topical form.
7 citations,
March 2022 in “Journal of the American Academy of Dermatology” Stress can trigger or worsen alopecia areata.
7 citations,
November 2014 in “Histochemistry and Cell Biology” The we/we wal/wal mice have defects in hair growth and skin layer formation, causing hair loss, useful for understanding alopecia.
6 citations,
May 2021 in “Journal of Health Sciences” Intravenous delivery of autologous activated platelet-rich plasma is safe.
6 citations,
January 2011 in “Journal of pediatric endocrinology & metabolism/Journal of pediatric endocrinology and metabolism” An 11-year-old Greek girl was diagnosed with a rare genetic disorder, highlighting the importance of genetic testing and family history.
4 citations,
December 2021 in “Experimental and Therapeutic Medicine” Adult female acne is complex and requires a combination of treatments for effective management.
3 citations,
March 2023 in “International journal of molecular sciences” Keratin protein production in cells is controlled by a complex system that changes with cell type, health, and conditions like injury or cancer.
2 citations,
April 2021 in “Naukovì gorizonti” Effective treatment significantly improves pododermatitis in dogs, reducing symptoms and extending remission.
2 citations,
January 2019 in “Skin appendage disorders” Higher social status is linked to earlier diagnosis and better treatment results for Frontal Fibrosing Alopecia in women.
Belimumab effectively controls SLE disease activity and reduces steroid use.
2 citations,
January 2016 in “Journal of Steroids & Hormonal Science” Women with PCOS and polycystic ovaries have higher male hormone levels and more insulin resistance, especially if they are overweight.
2 citations,
September 2011 in “InTech eBooks” The document outlines steps for moving fat from one body part to another.
1 citations,
May 2017 in “InTech eBooks” Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
June 2024 in “British Journal of Dermatology” The grand round helps improve diagnoses and suggests new treatments for hair disorders.
June 2024 in “British Journal of Dermatology” The review helps improve diagnosis and treatment of challenging hair disorders.
Using too much topical minoxidil can cause serious side effects like dizziness and low blood pressure.
November 2022 in “Skin health and disease” People with hair loss conditions often have more mental health issues like depression and anxiety compared to those without hair loss.
October 2022 in “Medical Clinical Update Journal” Early diagnosis and treatment with Leuprolide are key for children with precocious puberty.
Belimumab effectively reduces disease activity in lupus patients, regardless of initial serologic status.
Melampus might have cured Proetus' daughters, who possibly had ergotism or Cushing's syndrome, using the herb Helleborus niger, but a mix of factors could have caused their symptoms.