Depth and Patterns of Adnexal Involvement in Primary Extramammary (Anogenital) Paget Disease: A Study of 178 Lesions From 146 Patients
February 2016
in “
The American journal of dermatopathology/American journal of dermatopathology
”
TLDR Extramammary Paget disease can spread deeply into tissues, reaching up to 3.6 mm.
Extramammary Paget disease (EMPD) often involved adnexal structures, such as hair follicles and eccrine ducts, which facilitated deeper tissue spread. In a study of 178 lesions from 146 patients, the maximal depth of carcinomatous spread was 3.6 mm. This significant potential for deep spread should be considered when planning topical or novel local treatments for EMPD.
