November 2022 in “Journal of Nanobiotechnology” This study developed a scalable and high-throughput method for producing an injectable composite system combining platelet-rich plasma (PRP), cell-laden microcarriers, and hydrogels for hair follicle (HF) tissue engineering. The system, tested both in vitro and in vivo, significantly enhanced dermal papilla cell (DPC) proliferation, migration, and HF regeneration. In vivo experiments on mice showed that PRP-loaded microcarriers accelerated hair cycle transition and increased new hair follicle formation, with ~35 HFs and ~12 vessels per site. The findings suggest that this composite system could be a promising approach for treating hair loss and promoting hair growth through sustained release of growth factors and a conducive microenvironment.
November 2023 in “Biomaterials” Nanotechnology could improve hair regrowth but faces challenges like complexity and safety concerns.
16 citations,
November 2022 in “eLife” Both gene and non-gene areas of DNA evolved to make some mammals hairless.
Hairlessness in mammals is due to complex genetic changes in both genes and regulatory regions.
March 2023 in “World Journal of Biology Pharmacy and Health Sciences” Low levels of zinc and ferritin may be linked to the severity of alopecia areata in Iraqi patients.
September 2024 in “Journal of the American Academy of Dermatology” Estetrol (E4) may help treat female pattern hair loss by prolonging hair growth.
September 2022 in “Journal of Theoretical Biology” Hair follicles can regenerate after radiation damage but not during a specific growth phase.
18 citations,
November 2014 in “Journal of Agricultural and Food Chemistry” Brazilian propolis was found to speed up hair growth in mice by increasing the growth of skin cells that form hair.
9 citations,
August 2014 in “European journal of ophthalmology” PGF2α receptors in human eyelids are found in specific parts of hair follicles, explaining eyelash changes with glaucoma treatment.
9 citations,
September 2013 in “Journal of histochemistry and cytochemistry/The journal of histochemistry and cytochemistry” Matriptase is highly active in hair follicles and sebaceous glands, especially during hair growth phases.
14 citations,
July 2017 in “Fitoterapia” Oleanolic acid promotes hair growth by increasing cell proliferation through the Wnt/β-catenin pathway.
7 citations,
January 2016 in “Laboratory Investigation” TR3 is mainly found in hair follicle stem cells and may be involved in hair loss.
22 citations,
March 2009 in “Journal of Natural Medicines” Erica multiflora plant extract can help hair grow by stimulating growth-related cells and triggering hair cycle changes.
12 citations,
October 2018 in “Journal of Dermatological Science” Scientists made stem cells that can grow hair by adding three specific factors to them.
April 2024 in “International journal of research in dermatology” Azathioprine can cause hair loss and matted hair.
15 citations,
September 2016 in “Biochemical Journal” Wnt proteins from certain skin cells are crucial for normal hair growth and renewal.
218 citations,
January 2013 in “The Lancet Oncology” Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.
1 citations,
August 1994 in “Journal of Cutaneous Pathology” Hair loss happens due to faster cell growth and fewer cells in affected follicles.
170 citations,
January 2013 in “Journal of Investigative Dermatology” Wnt ligands are crucial for hair growth and repair.
46 citations,
January 2020 in “Theranostics” Injecting a special gel with human protein particles can help hair grow.
25 citations,
November 2012 in “Phytotherapy Research” Crataegus pinnatifida extract may help increase hair growth and thickness in mice.
1 citations,
January 2017 in “Springer eBooks” The document explains how hair follicles develop, their structure, and how they grow.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Mouse skin glands need healthy nerves to grow properly during hair growth phases.
26 citations,
October 2007 in “Experimental Dermatology” L-Carnitine-L-tartrate may help hair grow and prevent hair loss.
6 citations,
January 2017 in “Journal of toxicologic pathology” Rabbit skin with active hair growth shows thicker, redder areas due to larger, more numerous hair follicles and increased blood vessels.
88 citations,
September 2005 in “Journal of Dermatological Science” Versican, a protein, is less present in thinning hair follicles and this decrease might contribute to common hair loss in men.
Autophagy helps activate hair stem cells and hair growth by changing their energy use to glycolysis.
September 2023 in “Journal of Investigative Dermatology” Ganoderma lucidum extract and its component, ganoderic acid A, may effectively prevent hair loss.
Ganoderma Lucidum extract and ganoderic acid A can help prevent hair loss.