A Rare Case of Azathioprine Induced Anagen Effluvium and Plica Neuropathica

    April 2024 in “ International journal of research in dermatology ”
    Manish Rijhwani, M. Patel, Amrit Malik, Manisha Nijhawan
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    TLDR Azathioprine can cause hair loss and matted hair.
    A 16-year-old female developed anagen effluvium and plica neuropathica while on azathioprine, a rare occurrence. Anagen effluvium typically results from decreased metabolic activity in hair follicle matrix cells, often due to cancer treatments, while plica neuropathica involves irreversibly matted hair, usually linked to psychiatric issues, poor hair care, scalp infestations, or certain shampoos. This case highlights the potential for azathioprine to induce these conditions, expanding the understanding of its side effects.
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