research Reawakening GDNF's Regenerative Past in Mice and Humans
Activating the GDNF-GFRα1-RET signaling pathway could potentially promote skin and limb regeneration in humans and could be used to treat hair loss and promote wound healing.
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research Postpartum Telogen Effluvium Unmasking Traction Alopecia
Hair shedding after childbirth can reveal a pre-existing condition of hair loss due to tight hairstyles.
research An Open-Label Evaluator Blinded Study of the Efficacy and Safety of a New Nutritional Supplement in Androgenetic Alopecia: A Pilot Study
The supplement may help hair growth and is safe, but more research is needed.
research Clinical And Preclinical Approach In AGA Treatment: A Review Of Current And New Therapies In The Regenerative Field
New regenerative therapies show promise for treating hair loss.
research Autologous Stem Cell-Derived Therapies for Androgenetic Alopecia: A Systematic Review of Randomized Control Trials on Efficacy, Safety, and Outcomes
Stem cell therapies show promise for hair regrowth in androgenetic alopecia.
research A Missense Mutation in Lama3 Causes Androgen Alopecia
A gene mutation in Lama3 is linked to a common type of hair loss.
research Therapeutic Potential of Stem Cells in Follicle Regeneration
Stem cells, especially from fat tissue and Wharton's jelly, can potentially regenerate hair follicles and treat hair loss, but more research is needed to perfect the treatment.
research Revisiting the Role of Melatonin in Human Melanocyte Physiology: A Skin Context Perspective
Melatonin affects skin and hair color and protects skin cells, with potential benefits for hair growth and skin health.
research The Autoimmune Regulator (AIRE), Defective in Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy Patients, Is Expressed in Human Epidermal and Follicular Keratinocytes and Associates With the Intermediate Filament Protein Cytokeratin 17
AIRE protein, defective in APECED patients, is found in skin and hair cells and interacts with cytokeratin 17.
research Psychological Stress-Induced Pathogenesis of Alopecia Areata: Autoimmune and Apoptotic Pathways
Stress may contribute to hair loss in alopecia areata by affecting immune responses and cell death in hair follicles.
research Study of the Thyroid Profile of Patients with Alopecia
People with hair loss conditions may also have thyroid disorders, but more research is needed to understand the connection.
research The Biological Role of Platelet Derivatives in Regenerative Aesthetics
Platelet-derived products help regenerate tissue and are used in various skin and hair treatments.
research Alopecia Universalis Successfully Treated With Adalimumab
A woman with severe hair loss was successfully treated with the drug adalimumab.
research Network Pharmacology Reveals Curcuma Aeruginosa Roxb. Regulates MAPK and HIF-1 Pathways to Treat Androgenetic Alopecia
Curcuma aeruginosa Roxb. may help treat hair loss by affecting specific biological pathways.
research Forging the Future: 2018 Alopecia Areata Research Summit Summary Report
The summit concluded that new treatments like Jak inhibitors show promise for Alopecia Areata and personalized approaches are needed.
research Corticotropin-Releasing Hormone and the Skin
CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.
research Autophagy: Guardian of Skin Barrier
Autophagy helps keep skin healthy and may improve treatments for skin diseases.
research Skin Fibroblast Functional Heterogeneity in Health and Disease
Different types of skin fibroblasts have unique roles in skin health and disease.
research When The Circadian Clock Meets The Melanin Pigmentary System
Silencing certain circadian clock genes increases skin pigmentation.
research Brain-Derived Nerve Factor and Neurotrophins in Androgenetic Alopecia
Lower growth factors linked to balding in androgenetic alopecia.
research Peripheral Blood Gene Expression in Alopecia Areata Reveals Molecular Pathways Distinguishing Heritability, Disease, and Severity
Blood tests can help understand the genetic differences in people with alopecia areata, including how severe it is and if it's inherited.
research Understanding Autoimmunity of Vitiligo and Alopecia Areata
Both vitiligo and alopecia areata involve an immune response triggered by stress and specific genes, with treatments targeting this pathway showing potential.
research Understanding Skin Morphogenesis Across Developmental, Regenerative, and Evolutionary Levels
The article concludes that studying how skin forms is key to understanding skin diseases and improving regenerative medicine.
research Characterization of CD4+ Stem Cells of the Skin and Their Role in Skin Homeostasis and Tumorigenesis
CD4+ skin cells may be precursors to basal cell carcinoma.
research Building and Crossing the Translational Bridge: 2016 Alopecia Areata Research Summit Highlights
The summit aimed to speed up finding treatments for alopecia areata.
research Stem Cells in Dermatology and Anti-Aging Care of the Skin
Using defensins to activate stem cells may improve skin aging signs without causing inflammation.
research Brain And Muscle Arnt-Like Protein-1 (BMAL1) Controls Circadian Cell Proliferation And Susceptibility To UVB-Induced DNA Damage In The Epidermis
BMAL1 controls skin cell growth and UV damage risk, peaking at night.
research Role of OCT4 in the Regulation of FSH-Induced Granulosa Cell Growth in Female Mice
OCT4 helps granulosa cell growth in early-stage follicles, and FSH increases OCT4 through specific pathways.
research Bone Morphogenetic Protein Signaling Regulates Postnatal Hair Follicle Differentiation and Cycling
Blocking BMP signaling causes hair loss and disrupts hair growth cycles.
research Lgr5 Marks Cycling, Yet Long-Lived, Hair Follicle Stem Cells
Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.