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research Use of hair products in relation to ovarian cancer risk
In this study, frequent use of hair straighteners/relaxers and pressing products was associated with an increased risk of ovarian cancer, with potential variation in risk by tumor type noted for permanent hair dyes.
research Anti-Inflammatory, Thrombolytic and Hair-Growth Promoting Activity of the n-Hexane Fraction of the Methanol Extract of Leea indica Leaves
This study found that the n-hexane fraction from Leea indica leaves significantly increased hair growth in mice and showed potential as a natural treatment for alopecia.
research Spontaneous cutaneous adverse drug reaction reports—An analysis of a 10‐year dataset in Singapore
This study analyzed CADR reports in Singapore, finding nonsteroidal anti-inflammatory drugs, antibiotics, and iohexol frequently associated with serious skin reactions like rash and angioedema, with trends varying by demographics.
research Heat‐damaged evaluation of virgin hair
This study found that thermal hair-straightening devices significantly damaged the cuticle and cortex of virgin Asian and Caucasian hair, with Asian hair experiencing more protein loss than Caucasian hair.
research Synthesis, Biological Evaluation and Molecular Docking of Avicequinone C Analogues as Potential Steroid 5α-Reductase Inhibitors
This study found that a synthetic avicequinone C analogue, 5e, was significantly more potent in inhibiting steroid 5α-reductase type 1 activity in human keratinocytes compared to the original isolated compound.
research Essential of Hair Care Cosmetics
This review discusses the components and effects of various hair cosmetic procedures and explores new techniques like camouflage methods and tattoo scalp, without reporting new clinical results.
research Comprehensive Spectroscopic Characterization of Finasteride Polymorphic Forms. Does the Form X Exist?
This study found that the polymorphic forms I, II, and III of finasteride can be prepared purely, with form III being identical to what was previously referred to as form X.
research In vitro selective inhibition of human UDP-glucuronosyltransferase (UGT) 1A4 by finasteride, and prediction of in vivo drug–drug interactions
This study found that finasteride selectively inhibited UGT1A4 in vitro but is unlikely to cause clinically significant drug interactions mediated through hepatic UGT enzymes in vivo.
research Identification of a Cyclosporine-Specific P450 Hydroxylase Gene through Targeted Cytochrome P450 Complement (CYPome) Disruption in Sebekia benihana
This study found that regio-specific hydroxylation of cyclosporine A in Sebekia benihana is mediated by the cytochrome P450 hydroxylase CYP-sb21, suggesting potential biotechnological applications for hair growth promotion without immunosuppressive effects.
research Nanocarrier Systems for Transdermal Drug Delivery
Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.
research Modulation of the 6-position of benzopyran derivatives and inhibitory effects on the insulin releasing process
This study identified certain benzopyran derivatives with a bulky tert-butyloxycarbonylamino group as effective KATP channel openers that inhibit insulin secretion in rat pancreatic islets.
research Successful treatment of sebaceous adenitis in a rabbit with ciclosporin and triglycerides
This study found that a combination of ciclosporin and Miglyol 812 was effective in treating sebaceous adenitis in rabbits, with significant improvement in skin condition and hair regrowth.
research Development and ex-vivo skin permeation studies of finasteride–poly(lactic acid-co-glycolic acid) and minoxidil–chitosan nanoparticulate systems
This study found that finasteride- and minoxidil-loaded nanoparticles in a gel improved skin permeability and drug retention, suggesting a promising approach for topical alopecia treatment with reduced dosing frequency and side effects.
research Allergens of permanent hair dyes induces epidermal damage, skin barrier loss and IL-1 α increase in epidermal in vitro model
This study found that mixtures used in permanent hair dyes had irritant effects on reconstructed human epidermis, while individual ingredients alone did not.
research Testosterone in Women: Measurement and Therapeutic Use
This review discusses the limitations of serum androgen measurements in diagnosing and treating women with potential androgen-related disorders and the potential role of androgen replacement therapy for those with sexual interest/arousal disorders, reporting no new results.
research Increased dipicolinic acid production with an enhanced spoVF operon in Bacillus subtilis and medium optimization
In this study, the researchers successfully increased dipicolinic acid production in Bacillus subtilis by genetically modifying the spoVF operon, achieving a significant productivity improvement in the culture medium.
research Advancement in Shampoo (A Dermal Care Product): Preparation Methods, Patents and Commercial Utility
This article reviews various aspects of shampoos, including preparation methods and commercial value, but reports no new experimental results, instead focusing on patents and product evaluation criteria.
research Avaliação quantitativa em cortes histológicos transversais do couro cabeludo
This study reports that scalp biopsies in white adults usually have 16.5 hair follicles, primarily in the anagen phase, with male samples showing fewer follicular units but more fibrous tracts in certain areas.
research Effect of C-ring modifications in benzo[c]quinolizin-3-ones, new selective inhibitors of human 5α-reductase 1
This study found that octahydrobenzo[c]quinolizin-3-one derivatives, particularly compound 3, were potent and selective inhibitors of the enzyme 5α-reductase type 1.
research Dihydrotestosterone Induces Proliferation, Migration, and Invasion of Human Glioblastoma Cell Lines
This study found that testosterone may promote glioblastoma progression by being converted into dihydrotestosterone, which enhances cell proliferation, migration, and invasion in GBM cell lines.
research Anti-Zika Activity of a Library of Synthetic Carbohydrate Receptors
This study reports that synthetic carbohydrate receptors effectively inhibit Zika virus infection in cell cultures by blocking early stages of viral entry.
research Early plant growth and biochemical responses induced by Azospirillum brasilense Sp245 lipopolysaccharides in wheat (Triticum aestivum L.) seedlings are attenuated by procyanidin B2
In this laboratory study, procyanidin B2 inhibited early plant growth and biochemical responses in wheat seedlings treated with lipopolysaccharides from Azospirillum brasilense, suggesting that plant response activation requires LPS recognition by plant cells.
research Recent Advances in Drug Design and Drug Discovery for Androgen- Dependent Diseases
This review discusses various targets for treating prostate cancer and benign prostatic hyperplasia and reports on recent studies of new compounds and 5α-reductase inhibitors, but provides no new experimental results.
research Gender differences in scalp hair growth rates are maintained but reduced in pattern hair loss compared to controls
This study found that individuals with patterned hair loss, both male and female, showed a slower linear hair growth rate compared to controls with hair of equal thickness.
research Topical adenosine increases thick hair ratio in Japanese men with androgenetic alopecia
This study found that topical adenosine significantly increased the ratio of thick hairs and contributed to global improvement in Japanese men with androgenetic alopecia compared to niacinamide, with no observed adverse events.
research Distinct Conditions Support a Novel Classification for Bradykinin-Mediated Angio-Oedema
This study found multiple factors, both inherited and acquired, that may lead to bradykinin-mediated angio-oedema, proposing a new classification based on bradykinin production and catabolism imbalance.
research Chemoprevention of doxorubicin-induced alopecia in mice by dietary administration of l-cystine and vitamin B6
This study demonstrated that high doses of L-cystine and vitamin B6 effectively prevent doxorubicin-induced hair loss in mice.
research Drug eruptions in dermatology
This review covers various skin-related adverse drug reactions and lists common drugs associated with these reactions but presents no new clinical findings.
research Oral Testosterone With and Without Concomitant Inhibition of 5α-Reductase by Dutasteride in Hypogonadal Men for 28 Days
This study found that combining oral testosterone with dutasteride increased testosterone bioavailability in hypogonadal men while suppressing dihydrotestosterone levels over a 28-day period.