13 citations
,
October 2015 in “Journal of the European Academy of Dermatology and Venereology” The document concludes that early recognition and appropriate treatment of red scalp, red ear, and red scrotum syndromes can lead to remission.
12 citations
,
September 2013 in “BMC Biophysics” This study developed a model showing that keratin elasticity in skin may be influenced by electrostatic and bridging interactions between keratin filaments, contingent on the balance of charges in the surrounding medium.
12 citations
,
February 2010 in “Tetrahedron Letters” This article describes the synthesis of novel polyamine-modified minoxidil analogs and conjugates to potentially enhance minoxidil's biological activity, selectivity, and water solubility, but reports no new biological results.
11 citations
,
January 2016 in “Biointerphases” This study suggests that the outermost hair cuticle surface is rich in 18-methyleicosanic acid (18-MEA), supporting previous findings of its multilayer lipid and protein structure.
11 citations
,
January 2014 in “The Scientific World Journal” This study found that Cynatine HNS significantly improved hair and nail health in women after 90 days compared to placebo.
11 citations
,
July 2007 in “Journal of Hepatology” This study found a high prevalence of nonalcoholic fatty liver disease among women with polycystic ovary syndrome, with 41% of the participants affected.
11 citations
,
October 1997 in “British Journal of Dermatology” This study found that a serum-free culture system supported hair growth from follicles responsive to calcium, glucose, and amino acids, with insulin enhancing the growth, while other factors had no effect.
10 citations
,
February 2021 in “PLoS biology” This study found that corin, a protease, plays a crucial role in eccrine sweat glands by promoting sweat and salt excretion, which helps regulate electrolyte balance.
10 citations
,
October 2016 in “Journal of Biomolecular NMR” This study reported that using 2D solid-state NMR techniques on extensively labeled mouse fur improves resolution in detecting chemical shifts and secondary structure features, potentially aiding the analysis of the effects of commercial or therapeutic treatments on specific amino acids.
10 citations
,
March 2010 This chapter reviews various chemical synthesis methods for pharmaceutical compounds and reports no new experimental results.
10 citations
,
January 2010 in “PubMed” This article reviews current hair loss treatments, proposing a hypothesis that a combination of drugs, supplements, and therapies may effectively manage hair loss, but presents no new clinical results.
10 citations
,
January 2004 in “Dermatologic Surgery” This study found that storing hair follicle micrografts in HEPES-buffered DMEM with ACD inhibitors like aminoguanidine significantly increased hair shaft elongation compared to phosphate-buffered salt solution, suggesting improved viability for transplantation.
9 citations
,
November 2017 in “International Journal of Nanomedicine” This animal study found that intravenous administration of anionic squarticles, a lipid nanoemulsion, increased survival rates in rats with amitriptyline overdose by mitigating adverse effects and restoring normal blood pressure, highlighting its potential as a detoxifying antidote.
9 citations
,
November 2018 in “Acta Clinica Belgica” This case report suggests that spironolactone may induce prostate cancer proliferation in patients on abiraterone acetate, advising against its use for managing treatment-associated side effects in these individuals.
9 citations
,
January 2017 in “Organic Process Research & Development” This article describes the efficient synthesis of (S)-N-(2-bromo-6-methoxypyridin-4-yl)-2-hydroxy-2,4-dimethylpentanamide, a novel topical antiandrogen, with high purity and enantiomeric excess but reports no pharmacological results.
9 citations
,
July 2011 in “Scientific Reports” This study suggests that human evolution involved accelerated changes in the HR gene, affecting its role in mediating postnatal hair cycling.
9 citations
,
August 2007 in “Journal of animal science/Journal of animal science ... and ASAS reference compendium” This study observed that amino acid uptake into wool follicles varies significantly, with cysteine showing the highest uptake rate, suggesting specialized transport systems that may influence wool growth.
9 citations
,
January 1981 This study found that the alkaline degradation process of hair keratin using nucleophilic reagents led to different proportions of reaction products compared to wool, particularly more lanthionine and lysinoalanine residues.
9 citations
,
January 1959 in “The journal of nutrition/The Journal of nutrition” This study found that a higher potassium diet in lysine-deficient rats partially protected against hair loss and increased liver fat, suggesting these rats require more potassium.
8 citations
,
March 2020 in “Pain Medicine” This case report describes a woman with refractory trichodynia who became asymptomatic after receiving botulinum toxin type A injections, suggesting potential efficacy of this treatment for persistent trichodynia.
7 citations
,
June 2010 in “Bioorganic & medicinal chemistry letters” This study found that aminomethylpyrazole compound 10l inhibited hair growth in a mouse model and showed a low risk for photo-irritation, though it was slightly less effective than eflornithine.
7 citations
,
February 1998 in “Polymer journal” This study found that the stability of the coiled-coil structure in human hair keratin is maintained by ion-pairing and hydrophobic interactions, which are disrupted as pH approaches 7.0.
6 citations
,
December 2024 in “International Journal of Biological Macromolecules” This study introduced a novel exosome-loaded sprayable hydrogel (ADA-aPF127@LL18/Exo) that significantly enhanced wound healing in a deep partial thickness burn model, showing improved antibacterial efficacy and promoting tissue recovery processes like epithelialization and hair follicle regeneration.
6 citations
,
July 2018 in “Steroids” This study found that testosterone significantly influenced the expression and function of certain ion transporters in the vas deferens, impacting fluid secretion and contributing to a suitable environment for male fertility.
6 citations
,
January 2016 in “Bioorganic & Medicinal Chemistry Letters” This study reported that certain minoxidil conjugates, specifically those with spermine, methylenedianiline, and diaminofluorene, were able to induce differentiation in HL-60 acute myeloid leukemia cells without toxicity at a concentration of 10 μM.
6 citations
,
July 1975 in “Archives of Dermatology” This case report discusses two female patients experiencing significant hair loss, potentially linked to a weight loss regimen involving chorionic gonadotropin injections.
5 citations
,
April 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This article discusses junctional epidermolysis bullosa caused by COL17 deficiency, noting a lack of experimental therapies and the impact of nonsense mutations, but it reports no new clinical results.
5 citations
,
February 2022 in “Biophysical journal” This study developed a mathematical model indicating that the amino acid sequences of intermediate filament proteins, rather than flexibility differences, significantly impact assembly rates.
5 citations
,
January 2016 in “Genetics and Molecular Research” This study identified 617 differentially expressed genes in cashmere goat hair follicles, which are involved in key biological processes and provide insights into hair follicle development.
5 citations
,
June 2013 in “Fashion business” This study found that adding rose hip extract to permanent wave solutions increased wave effectiveness and reduced hair damage, although variations in hair type may affect the results.