research Alpha-Parvin Is Required for Epidermal Morphogenesis, Hair Follicle Development, and Basal Keratinocyte Polarity
α-parvin is necessary for skin and hair growth and for the correct orientation of skin cells.
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research Protein Kinase Akt2/PKBβ Is Involved in Blastomere Proliferation of Preimplantation Mouse Embryos
Akt2 protein is essential for normal cell division in early mouse embryos.
research Secretory Phospholipase A2-IIA Overexpressing Mice Exhibit Cyclic Alopecia Mediated Through Aberrant Hair Shaft Differentiation and Impaired Wound Healing Response
Mice with too much sPLA₂-IIA have hair loss and poor wound healing due to abnormal hair growth and stem cell depletion.
research Plasma Rich in Growth Factors for the Treatment of Androgenetic Alopecia
PRGF treatment safely and effectively helps hair loss.
research Promotion of Mouse Ameloblast Proliferation by Lgr5 Mediated Integrin Signaling
CD61 is important for mouse tooth cell growth and works through Lgr5.
research Pigmentation Effect of Rice Bran Extract in Hair Follicle-Like Tissue and Organ Culture Models
Rice bran extract boosts melanin production in hair follicles.
research The Effect of 1540-nm Fractional Erbium-Glass Laser in the Treatment of Androgenic Alopecia
Laser treatment effectively increases hair density and thickness in androgenic alopecia.
research Functional Analysis of VDR Gene Mutation R343H in a Child with Vitamin D-Resistant Rickets with Alopecia
The R343H mutation in the VDR gene causes vitamin D-resistant rickets with alopecia by impairing specific gene activity.
research Runx Family Genes in Tissue Stem Cell Dynamics
Runx genes are important for stem cell regulation and their roles in aging and disease need more research.
research Dermal-Epidermal Cross-Talk: Differential Interactions With Microvascular Endothelial Cells
Human dermal fibroblasts help microvascular endothelial cells grow, but not vice versa.
research Early Dengue Virus Infection in Human Skin: A Cycle of Inflammation and Infectivity
Chicken feather gene mutation helps understand human hair disorders.
research Exposure to Gamma-Rays at the Telogen Phase of the Hair Cycle Inhibits Hair Follicle Regeneration at the Anagen Phase in Mice
Gamma-rays exposure during the resting phase of hair growth can damage hair regeneration and color in mice.
research Comparative Gene Expression Profiling of Senescent and Androgenetic Alopecia Using Microarray Analysis
SA linked to mitochondrial issues and oxidative stress, while AGA involves disrupted hair growth genes.
research Hair Graying Regulators Beyond Hair Follicle
Hair graying is influenced by factors like nerves, fat cells, and immune cells, not just hair follicles.
research Glioblastoma Cells Express Crucial Enzymes Involved in Androgen Synthesis: 3β-Hydroxysteroid Dehydrogenase, 17-20α-Hydroxylase, 17β-Hydroxysteroid Dehydrogenase, and 5α-Reductase
Glioblastoma cells can make androgens, which might help the tumor grow.
research Evaluation of Adding Platelet-Rich Plasma to Combined Medical Therapy in Androgenetic Alopecia
Adding platelet-rich plasma improves hair density and thickness in androgenetic alopecia.
research Clascoterone as a Novel Treatment for Androgenetic Alopecia
Clascoterone may be a promising treatment for hair loss.
research Skin Biology
Current therapies cannot fully regenerate adult skin without scars; more research is needed for scar-free healing.
research Testosterone Down-Regulates Expression of αVβ3-Integrin, E-Cadherin, and Mucin-1 During Uterine Receptivity Period in Rats
Testosterone reduces key molecules needed for early pregnancy in rats.
research A Guide for Building Biological Pathways with Two Case Studies: Hair and Breast Development
The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.
research Function of KLF4 in Stem Cell Biology
KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.
research Hair-Cycle Dependent Differential Expression of ADAM 10 and ADAM 12
ADAM 10 and ADAM 12 proteins are involved in different stages of hair growth and could be targets for treating hair disorders.
research Inhibition of T-Cell Activity in Alopecia Areata: Recent Developments and New Directions
New treatments targeting T-cell pathways are needed for better alopecia areata management.
research Integrated Transcriptomics and Metabolomics Analyses of Stress-Induced Murine Hair Follicle Growth Inhibition
Chronic stress in mice changes skin metabolism and gene expression, leading to hair loss.
research Evaluation of Efficacy of Intradermal Injection Therapy vs Derma Roller Application for Administration of QR678 Neo Hair Regrowth Formulation for the Treatment of Androgenetic Alopecia—A Prospective Study
Intradermal injections improve hair density and thickness better, while derma roller is more convenient.
research Mapping of Cis-Acting Expression Quantitative Trait Loci in Human Scalp Hair Follicles
Researchers identified genes in scalp hair follicles that may affect hair traits and hair loss.
research Autologous Activated Platelet-Rich Plasma in Hair Growth: A Pilot Study in Male Androgenetic Alopecia with In Vitro Bioactivity Investigation
PRP treatment significantly increased hair density and thickness in male hair loss.
research Computational Derivation of a Molecular Framework for Hair Follicle Biology from Disease Genes
The research provides a gene-based framework for hair biology, highlighting the Hippo pathway's importance and suggesting links between hair disorders, cancer pathways, and the immune system.
research Early-Onset Baldness and the Risk of Aggressive Prostate Cancer: Findings from a Case-Control Study
Men who start balding at age 20 may have a higher chance of getting aggressive prostate cancer.
research Estrogen Modulates Mesenchymal-Epidermal Interactions in the Adult Nipple
Estrogen is important for keeping adult mouse nipple skin healthy by controlling certain cell signals.