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Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

UVB radiation changes the chemical makeup and dries out human hair but doesn't alter its appearance or texture.

Honokiol might help reduce male skin aging by maintaining testosterone levels.

The 3D structure of a key hair protein was modeled, revealing specific helical structures and stabilization features.

The document concludes that certain mutations may contribute to the inflammation in hidradenitis suppurativa and suggests that targeting TNFα could be a treatment strategy.

Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.

Hidradenitis Suppurativa has genetic links, with certain gene mutations more common in patients and a third of cases having a family history.

Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

The L457(3.43)R mutation in the human lutropin receptor causes increased activity and hormone insensitivity, leading to precocious puberty.

The vitamin D receptor helps maintain hair and bone health even without binding vitamin D.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Modern hair transplants use small grafts for a natural look and drugs to prevent further loss, with high patient satisfaction.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

The African spiny mouse can fully regenerate its muscle without scarring, unlike the common house mouse.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Whale genes show changes that help them live in water, like less hair and better flippers.

A rare ITGB6 gene variant causes intellectual disability, hair loss, and dental issues.

Hair's strength and flexibility come from its protein structure and molecular interactions.

Electrostatic interactions mainly stabilize the binding of peptides to hair keratin.