Search
for
Sort by
Research
180-210 / 1000+ results
research Topical latanoprost acid for female androgenetic alopecia: a pilot proof-of-concept trial with mechanistic evidence of FP-receptor activation
In this study, topical latanoprost acid applied daily for 6 months increased hair count and improved trichoscopic markers among women with hair loss, suggesting its potential for treating female androgenetic alopecia, particularly at a 0.05% concentration.
research α-spinasterol from Melandrium firmum attenuates benign prostatic hyperplasia in a rat model
This study found that α-spinasterol treatment significantly reduced testosterone propionate-induced prostatic hyperplasia in rats, suggesting potential benefits for managing benign prostatic hyperplasia.
research Synthesis, Characterization and Evaluation of 5α, 6β-Dihalo Androsterone Derivatives as 5α-Reductase Inhibitors
This study found that the synthesized compound 7b exhibited higher 5α-reductase inhibitory activity, increased solubility, and dissolution compared to finasteride, suggesting its potential as a lead compound for benign prostatic hyperplasia treatment.
research Proton Affinitive Derivatization for Highly Sensitive Determination of Testosterone and Dihydrotestosterone in Saliva Samples by LC-ESI-MS/MS
This study reported that derivatization with 5-butylpicolinic acid improved the sensitivity for detecting testosterone and DHT in saliva using LC-ESI-MS/MS, with minimal interference from the saliva matrix.
research Historical and Current Adenosine Receptor Agonists in Preclinical and Clinical Development
This review discusses the development and potential therapeutic applications of adenosine receptor agonists and positive allosteric modulators, noting that while many clinical trials have been unsuccessful, initial results for new compounds are promising.
research Biotransformation of Finasteride (MK-0906) by Selenastrum capricornutum (Green Algae)
Green algae can break down finasteride, reducing environmental harm.
research Comportamiento de la estructura financiera de un grupo de empresas españolas previa a la participación del capital-riesgo
This study found that compound 2 from Polygonum multiflorum increased dermal papilla cell proliferation and vibrissa follicle hair-fiber length more effectively than minoxidil in vitro, suggesting potential for alopecia treatment.
research EVALUATION OF HEPATOPROTECTIVE ACTIVITY OF AMALGAMATION OF KUTKUTI (TRIDAX PROCUMBENS) AND GINGER JUICE AGAINST PARACETAMOL INDUCED HEPATOTOXICITY IN RATS.
This study reported that the combination of tridax procumbens and ginger juice improved antioxidant activity and protected against liver damage induced by paracetamol in rats, suggesting a potent hepatoprotective effect.
research A liquid chromatography/tandem mass spectrometry method for determination of aristolochic acid‐I in rat plasma
This study developed and validated a sensitive liquid chromatography–mass spectrometry method to measure aristolochic acid‐I in rat plasma, successfully applying it to pharmacokinetic research.
research Dutasteride mesotherapy in the treatment of androgenetic alopecia
Dutasteride injections can help treat hair loss in men and women.
research Microalgae, Tetraselmis tetrathele has Alopecia Prevention and Scalp Improvement
This study found that an ethanolic extract from the microalga Tetrathelmis tetrathele exhibited anti-inflammatory effects, promoted the proliferation of certain skin and hair cells, and inhibited 5α-reductase activity, suggesting its potential as a therapeutic agent for preventing alopecia and enhancing scalp health.
research Bioactives in Chinese Proprietary Medicine Modulates 5α-Reductase Activity and Gene Expression Associated with Androgenetic Alopecia
This study found that several compounds from Yangxue Shengfa capsule may promote hair growth by enhancing cell proliferation in vitro, suggesting potential use in treating androgenetic alopecia.
research EFICÁCIA DO PLASMA RICO EM PLAQUETAS PARA O TRATAMENTO DE ALOPÉCIA ANDROGENÉTICA
This review found that platelet-rich plasma treatment is effective for androgenetic alopecia, significantly increasing hair diameter in both sexes, but only improving hair density in men.
research Crystal Structure and Synthesis of 17α-Acetoxy-4-bromopregn-4-ene-3,20-dione
The document concludes that a compound with potential for treating prostate cancer and hair loss was successfully made and its detailed structure was confirmed.
research Efficacy and tolerance of 2,3-diphenylcyclopropenone in propylene glycol versus 2,3-diphenylcyclopropenone in isopropanol – a novel formula designed for the treatment of alopecia areata
This study found that both new and old formulas of DCP for treating alopecia areata resulted in similar hair regrowth, but tolerance was significantly better with DCP in isopropanol.
research [Two drugs have a better outcome. Finasteride plus alpha blocker improves urine flow].
research Pharmacodynamics and pharmacokinetics of P-3074, a new finasteride topical solution, administered at four different doses
P-3074 effectively blocks scalp DHT better than oral finasteride.
research Mechanism of PPARα agonist in alopecia areata
This study found that PPARα agonists provided protective effects in mouse models of alopecia areata by promoting early reversal of the condition and inhibiting T effector cell function, indicating potential therapeutic value for this inflammatory condition.
research Topical Immunotherapy with Diphenylcyclopropenone in Paediatric Patients with Alopecia Areata—A Retrospective Study of 97 Patients
Among pediatric alopecia areata patients treated with DPCP, this study reported complete hair regrowth in 8.8% and any regrowth in 61.8% after one year, with better outcomes for those with milder initial symptoms and longer treatment durations.
research Use of diphenylcyclopropenone for alopecia areata treatment during pregnancy
This article reviews DPCP's use as a topical immunotherapy for alopecia areata and discusses its suggested mechanism, but reports no clinical results.
research Extemporaneous Topical Minoxidil Solutions for the Treatment of Androgenetic Alopecia- Stability Studies and Incorporation Tests of Active Pharmaceutical Ingredients in Aloplus Total Base.
This study reported that minoxidil lotions produced using a propylene glycol-free base, Aloplus Total, demonstrated high minoxidil solubility and maintained chemical and physical stability for over 180 days, suggesting suitability for enhanced topical treatments of androgenetic alopecia.
research Relationship between neonatal allopregnanolone and neonatal stress: effects on adolescent and adult behaviour /
This study found that neonatal administration of Allopregnanolone may mitigate some behavioral effects of early maternal separation in adolescence, but also lead to similar adverse effects as the separation in adulthood.
research Standardization of Eclipta Alba by HPTLC, HPLC and AAS
This study found petroleum ether to be more effective than methanol at extracting β-sitosterol from Eclipta alba, with higher concentrations detected using HPTLC and HPLC methods. The extracted materials contained metals within safety limits.
research Abstract P5-21-05: ERALOP study: Post adjuvant FEC - docetaxel chemotherapy for early breast cancer: Hair regrowth in the real life
This study found that persistent significant alopecia was a common side effect following FEC-docetaxel chemotherapy, with a 33.4% global incidence, highlighting the need for awareness and potential preventative measures like cooling caps during treatment.
research The Antiepileptic and Antidepressant-Like Effects of Dexpanthenol in Female Swiss Albino Mice
In this study, dexpanthenol exhibited antiepileptic and antidepressant-like effects in mice without impacting their motor coordination.
research 40gm 미만의 전립선비대증에서 α-차단제와 Finasteride 병합요법의 유용성
Combining α-blockers and Finasteride is useful for treating small prostate enlargement.