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      Drug Discovery Today: Therapeutic Strategies - 2006 Editorial

      research Drug Discovery Today: Therapeutic Strategies - 2006 Editorial

      March 2006 in “Drug Discovery Today: Therapeutic Strategies”
      The 2006 editorial concluded that immunotherapy was advancing with new drugs, focusing on specific biological therapies and convenient oral treatments, and highlighted the importance of partnerships and new regulations in the field.
      Vitamin D and Human Health: Lessons from Vitamin D Receptor Null Mice

      research Vitamin D and Human Health: Lessons from Vitamin D Receptor Null Mice

      1533 citations , October 2008 in “Endocrine reviews”
      This research highlights that engineered mice lacking the vitamin D receptor show multiple health issues similar to human vitamin D deficiency, underscoring the widespread impacts of the vitamin D endocrine system.
      Mechanisms Regulating Skin Immunity and Inflammation

      research Mechanisms regulating skin immunity and inflammation

      610 citations , April 2014 in “Nature Reviews Immunology”
      This review discusses the complex mechanisms regulating skin immunity to balance host defense with inflammation, but reports no new findings.
      Vitiligo: A Comprehensive Overview

      research Vitiligo: A comprehensive overview

      532 citations , August 2011 in “Journal of the American Academy of Dermatology”
      This article discusses the clinical presentation, histopathologic findings, and pathogenesis hypotheses of vitiligo without reporting new clinical results.
      Alopecia Areata: An Autoimmune Disease Causing Hair Loss

      research Alopecia Areata

      421 citations , April 2012 in “The New England Journal of Medicine”
      Alopecia Areata is an autoimmune condition causing hair loss with no cure and treatments that often don't work well.
      Alopecia Areata Update

      research Alopecia areata update

      391 citations , January 2010 in “Journal of The American Academy of Dermatology”
      This article reviews the clinical presentation and histopathologic features of alopecia areata and proposes a hypothesis for its development, but it reports no new clinical results.
      Alopecia Areata: Overview and Insights from January 2018

      research Alopecia areata

      290 citations , December 2017 in “Journal of The American Academy of Dermatology”
      This article reviews the epidemiology, clinical evaluation, and pathogenesis of alopecia areata and highlights recent advancements, but it does not report new clinical findings.
      Dermatoses of Pregnancy

      research Dermatoses of pregnancy

      208 citations , July 2001 in “Journal of The American Academy of Dermatology”
      This review discusses the classification and diagnosis of pregnancy-related skin conditions and reports no new clinical findings.
      Alopecia Areata: A Review of Disease Pathogenesis

      research Alopecia areata: a review of disease pathogenesis

      191 citations , May 2018 in “British journal of dermatology/British journal of dermatology, Supplement”
      This study reviewed recent theories on alopecia areata's pathogenesis, highlighting its autoimmune nature due to immune privilege disruption in hair follicles, and noted current treatments have limited efficacy with high relapse rates, underscoring the need for further research into its mechanisms for better therapies.
      S1 Guideline on Post-COVID/Long-COVID

      research S1-Leitlinie Post-COVID/Long-COVID

      156 citations , September 2021 in “Pneumologie”
      This review discusses the development of an interdisciplinary guideline on Post-COVID/Long-COVID symptoms, diagnostics, and therapies by the Deutsche Gesellschaft für Pneumologie, reporting no new results but highlighting ongoing updates based on emerging knowledge.
      The Pathogenesis of Primary Cicatricial Alopecias

      research The Pathogenesis of Primary Cicatricial Alopecias

      150 citations , October 2010 in “The American Journal of Pathology”
      This review discusses the pathogenesis and challenges in treating primary cicatricial alopecia, highlighting the need to understand immune protection collapse in hair follicle stem cells; it reports no new clinical results.
      Cutaneous Lupus Erythematosus: A Review

      research Cutaneous lupus erythematosus: a review

      149 citations , July 2002 in “Dermatologic clinics”
      This review discusses the pathogenesis, clinical presentation, diagnosis, and treatment of cutaneous lupus erythematosus, reporting no new clinical findings.
      Alopecia Areata: A Multifactorial Autoimmune Condition

      research Alopecia areata: A multifactorial autoimmune condition

      148 citations , December 2018 in “Journal of autoimmunity”
      This review discusses genetic and environmental factors contributing to autoimmunity in alopecia areata and reports no new clinical findings, emphasizing the need for further study on its aetiology and pathophysiology.
      The IL-23/IL-17 Pathway in Inflammatory Skin Diseases: From Bench to Bedside

      research The IL-23/IL-17 Pathway in Inflammatory Skin Diseases: From Bench to Bedside

      144 citations , November 2020 in “Frontiers in immunology”
      This study summarizes how the IL-23/IL-17 axis contributes to inflammatory skin diseases like psoriasis and highlights that biologics targeting this pathway, including monoclonal antibodies against IL-23 and IL-17, have shown efficacy in clinical trials for these conditions.
      Tregs: Where We Are and What Comes Next?

      research Tregs: Where We Are and What Comes Next?

      130 citations , November 2017 in “Frontiers in Immunology”
      This review explores recent findings on regulatory T cells, focusing on their unique functions in non-lymphoid tissues and new mechanisms of action, but presents no original clinical results.
      Cutaneous Manifestations of Systemic Lupus Erythematosus

      research Cutaneous manifestations of systemic lupus erythematosus

      127 citations , September 1996 in “British Journal of Dermatology”
      This study found that cutaneous signs such as chilblains and urticaria were notably common in British patients with systemic lupus erythematosus, while subacute cutaneous lesions were less frequent.
      Regulatory T Cells: The Many Faces of Foxp3

      research Regulatory T Cells: the Many Faces of Foxp3

      125 citations , September 2019 in “Journal of Clinical Immunology”
      This review summarizes recent advances in Treg cell biology, focusing on Foxp3's role in immune regulation and therapeutic reprogramming for immune dysregulatory disorders, but reports no new clinical results.
      The Human Hair: From Anatomy to Physiology

      research The human hair: from anatomy to physiology

      107 citations , December 2013 in “International Journal of Dermatology”
      This review summarizes the anatomical and physiological aspects of human hair and its clinical significance, but does not report new research findings.
      Hair Follicle Immune Privilege Revisited: The Key to Alopecia Areata Management

      research Hair Follicle Immune Privilege Revisited: The Key to Alopecia Areata Management

      102 citations , December 2017 in “˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings”
      This review discusses the role of immune privilege collapse in the pathogenesis of alopecia areata, emphasizing the potential for therapeutic manipulation of hair bulb immune privilege to offer new treatment options, and reports no new results.
      Alopecia Areata: A Comprehensive Review of Pathogenesis and Management

      research Alopecia Areata: a Comprehensive Review of Pathogenesis and Management

      99 citations , July 2017 in “Clinical Reviews in Allergy & Immunology”
      This review noted that alopecia areata is an autoimmune disease impacting hair follicles and offered insights into its complex pathogenesis involving immune responses, while highlighting ongoing research into new treatments such as Janus kinase inhibitors and other immunomodulatory drugs.
      Neuroendocrinology of the Hair Follicle: Principles and Clinical Perspectives

      research Neuroendocrinology of the hair follicle: principles and clinical perspectives

      98 citations , July 2014 in “Trends in Molecular Medicine”
      This article discusses the role of human hair follicles in neuroendocrinology and suggests potential new therapeutic targets by examining how neuromediators influence hair growth, pigmentation, and stem cell biology in organ cultures.
      S1 Guideline Long/Post-COVID

      research S1-Leitlinie Long-/Post-COVID

      96 citations , December 2022 in “Pneumologie”
      This guideline review discusses current symptoms, diagnostic approaches, and treatments for Long- and Post-COVID, based on today's knowledge, and emphasizes its practical application with ongoing updates as new insights emerge.