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Blocking allopregnanolone production in mice makes them more anxious after stress, but this can be reversed with a drug that mimics allopregnanolone.

Benzothiazepines like diltiazem reduce anxiety in mice by making neurosteroids.

Mild exercise reduces pain in older rats through a brain chemical, while intense exercise reduces pain in all rats through a different pain-blocking process.

Finasteride affects alcohol intake in male mice, possibly due to neurosteroids.

Paeoniflorin protects brain cells by involving a specific protein and neurosteroids.

New genes and pathways are important for testosterone production and male sexual development.

A brain-produced steroid causes increased scratching in mice with a skin condition similar to eczema.

Finasteride worsens stress effects on sensory processes, possibly linking to anxiety/depression.

Changing neuroactive steroids in baby male rats affects their memory and learning differently as they grow up.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Minoxidil prevents serotonin loss from MDMA by affecting potassium channels and increasing Akt phosphorylation.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

Finasteride reduces alcohol withdrawal severity and anxiety in mice, but may increase withdrawal severity in some cases.

Finasteride helps protect brain in old male rats.

Three drugs change mice's alcohol drinking patterns by affecting GABAA receptors.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Egg shell membrane hydrolysates can reduce wrinkles and improve skin health.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Finasteride may cause long-lasting sexual side effects.

Androgens play a role in female sexual function, and testosterone therapy can help women with low sexual desire, but more research is needed on treatments and long-term safety.

Neurosteroids show promise for treating epilepsy and more research is needed.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

Minoxidil effectively treats female pattern hair loss.