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Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

A mother and son both had ulcerative colitis and alopecia, suggesting a genetic link in autoimmune disorders and successful treatment with cyclosporine.

Most hirsutism cases are due to PCOS, and treatment focuses on lowering testosterone and blocking its effects.

Different combinations of human hair keratins affect how hair fibers form.

Lipopolysaccharides boost wheat seedling growth, but procyanidin B2 weakens this effect.

Copper and iron cause keratin damage in hair by converting methionine to homocysteine.

Keratin proteins are consistent across different hair types from the same person.

Terazosin and finasteride together cause no major issues.

Adding L-glutamine to the diet of Hanwoo steers may boost their immune system and help them cope with heat.

Vav2 and Vav3 proteins help control skin stem cell numbers and activity in both healthy and cancerous cells.

Kolaviron and quercetin may help treat prostate issues.

PSA can help diagnose high androgen levels in women.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Visible light can damage skin and most sunscreens don't block it well; more research is needed on its effects and protection methods.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

The study found that two enzymes linked to hair loss are located in different parts of the scalp, supporting a common treatment's effectiveness.

Finasteride effectively blocks rat enzymes, but with varying methods and strength.