This review explores the extraction, characterization, and skin cosmetic effects of phenolic compounds and pigments from marine macroalgae, highlighting their documented benefits for skin health, such as whitening, moisturizing, photoprotection, and anti-aging effects, without adverse health impacts.
70 citations
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July 2016 in “Aging” This study suggests that dermal adipocytes might play a key role in skin aging due to their transformation into fibrotic structures in chronically photo-damaged skin.
20 citations
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June 2015 in “Hormone Molecular Biology and Clinical Investigation” This study found that long-term finasteride therapy in men with BPH worsened erectile dysfunction and reduced testosterone levels, while these effects were not observed with tamsulosin.
8 citations
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November 2020 in “Journal of Cosmetic Dermatology” This preclinical study observed that a nanoencapsulated ingredient complex, AcPi, may prevent hair follicle aging and hair loss by reducing oxidative stress, enhancing mitochondrial activity and WNT/β-catenin signaling, and controlling androgenic metabolism when tested on human scalp cultures.
5 citations
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January 2025 in “Aesthetic Surgery Journal Open Forum” In this mouse study, researchers reported that sequential monopolar-bipolar radiofrequency irradiation significantly improved skin quality by increasing collagen density, elastin fiber expression, and fibroblast differentiation more than monopolar RF treatment alone.
1 citations
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September 2023 in “Stem cell research & therapy” This review discusses how mesenchymal stromal cell-based therapy holds promise for treating age-related diseases, given its potential to target aging's pathological features, although significant challenges remain for its clinical application.
December 2025 in “Dietetics” This paper reviewed studies from 2019 to 2025 on the use of olive oil and other derivatives from the European olive tree for skin, hair, and nail care, noting their roles in wound healing and skin aging while highlighting a favorable safety profile.
September 2024 in “Journal of Investigative Dermatology” This study developed a deep learning-based tool to quantify individual hair fibers in mice, revealing distinct hair phenotypes linked to hormonal, genetic, and age-related factors, and suggesting its potential for new diagnostic methods through hair analysis.
April 2018 in “Journal of Investigative Dermatology” This study found that Anigozanthos Flavidus flower extract may improve skin elasticity and reduce wrinkles by increasing essential extracellular matrix proteins in both in vitro and in vivo settings.
67 citations
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May 2016 in “Journal of Cosmetic Dermatology” This study describes commonly used peptides, proteins, and growth factors in cosmeceuticals and discusses their potential benefits in dermatology, though their long-term effects remain unconfirmed.
22 citations
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November 2024 in “Planta” This review highlights the potential of aromatic plants as natural antioxidants in cosmeceuticals, which may combat skin aging and promote rejuvenation by counteracting oxidative stress, offering a natural alternative to synthetic products with benefits like photoprotection and anti-wrinkle effects.
17 citations
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September 2024 in “Journal of Ginseng Research” This review discusses recent in vitro and in vivo research suggesting that components of ginseng, such as ginsenosides and gintonin, may have potential skincare benefits, including anti-aging effects and treatment of skin conditions like atopic dermatitis and hypertrophic scars.
1 citations
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September 2013 in “Elsevier eBooks” This review discusses factors affecting hair aging, such as inflammation and UV exposure, and examines potential anti-aging benefits of antioxidants and nutraceuticals for hair, but reports no new clinical results.
May 2026 in “Applied Sciences” In this review, the authors reported that sprout extracts, rich in bioactive compounds, show promising effects on skin health, such as enhancing collagen synthesis, improving hydration, and reducing inflammation, though most evidence comes from laboratory and animal studies.
This review found that exposure to pollutants like PM, NOx, and PAHs is linked to various skin and hair disorders, indicating a need for cosmetics with natural adsorbents to reduce pollutant effects, achieving 30-55% removal efficiency.
August 2025 in “International Journal for Research in Applied Science and Engineering Technology” In this study, rice water was reviewed as a cosmetic ingredient, highlighting its safety, stability, and possible benefits such as anti-inflammatory and anti-aging effects, as well as improvements in hair growth and skin hydration.
April 2024 in “Biomolecules” This review summarizes recent findings on the role of mesenchymal stem cell-derived exosomal microRNAs in skin regeneration and rejuvenation, discussing their potential for treating skin damage and aging, and exploring bioengineering methods to enhance therapeutic effects.
This study explored the potential of custard apple extract in an herbal hair conditioner to improve smoothness, aid brushing, and provide other cosmetic benefits, including lice removal and anti-aging effects.
December 2023 in “Anti-Aging Eastern Europe” This review discusses the interplay between polycystic ovary syndrome, aging, and fertility in women, and reports no new clinical results; the authors highlight pathways and interventions needing further research.
13 citations
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May 2024 in “Frontiers in Aging” This article reviews how stem cell exhaustion contributes to aging, emphasizing the balance between proliferation and quiescence as crucial for long-term stem cell maintenance, but it reports no new results.
119 citations
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August 2010 in “Journal of Investigative Dermatology” This study reports that 11β-HSD1 activity in human skin increases with age and photoexposure, potentially contributing to skin aging and the effects of glucocorticoids.
60 citations
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January 2023 in “Biogerontology” This review examines testosterone's role in male health and aging but reports no new clinical results; the authors highlight the need for further research on optimal testosterone levels to prevent age-related conditions.
1 citations
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April 2016 in “CRC Press eBooks” Skin aging reflects overall body aging and can indicate internal health conditions.
December 2025 in “Pharmaceutics” In this study, araliadiol, a plant-derived compound, exhibited senomorphic effects in three dermal fibroblast senescence models, suggesting its potential as a topical treatment to mitigate skin aging by reducing certain senescence-related markers and increasing procollagen type I content.
77 citations
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July 2013 in “Best Practice & Research in Clinical Obstetrics & Gynaecology” This review discusses the impact of menopause-related oestrogen deficiency on skin ageing and suggests that oestrogen use may improve collagen and skin elasticity, but it reports no clinical trial results.
74 citations
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January 1998 in “Dermatology” This study reported that men with more significant hair loss experience greater negative psychosocial effects, particularly noticeable in younger age groups.
67 citations
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August 2013 in “International Journal of Cosmetic Science” This review discusses the role of oxidative stress in hair greying and suggests that understanding melanocyte susceptibility at different follicular locations may help develop therapies for preventing and reversing the process; it reports no new experimental results.
20 citations
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July 2015 in “Journal der Deutschen Dermatologischen Gesellschaft” This review summarizes the anticarcinogenic, anti-inflammatory, and other health effects of green tea, noting its historical and ongoing use in dermatological and cosmeceutical applications, but reports no new clinical results.
16 citations
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January 2019 in “Aging” This study found that transgenic mice expressing a mutant CYLD protein lacking deubiquitinase function showed signs of premature aging and spontaneous tumor development, likely due to over-activation of specific molecular pathways and chronic inflammation.
13 citations
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October 2007 in “Bulletin of the Korean Chemical Society” This article reviews mollugin's reported biological activities, including its potential for various therapeutic and cosmetic applications such as anti-tumor effects and hair growth stimulation, but presents no new experimental data.