Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

Paclitaxel chemotherapy causes premature aging and damage to hair follicles, potentially leading to permanent hair loss.

This article reviews the effect of aging on male hormone levels and fertility, highlighting the need for more research on the benefits and risks of androgen supplementation in older men.

This review discusses the protective effects and mechanisms of melatonin in skin and suggests potential therapeutic applications in cutaneous medicine, reporting no new clinical findings.

In this study, anabolic and catatoxic steroids were reported to prevent weight loss, tissue calcification, and cardiac necrosis in a rat model of disturbed calcium metabolism and progeria-like syndrome.

This source summarizes discussions by an advisory board of twelve experts on hair loss, focusing on heredity, aging, and environmental impacts, and emphasizing strategies that may slow alopecia.

This review discusses the classification and regulation challenges of anti-ageing cosmetics in Europe and reports no new findings; it calls for increased transparency to help consumers make informed choices.

This study found that sustained intracellular acidosis in mice was associated with shortened lifespan, early aging signs, and impaired autophagy.

This study found that glycolic acid treatment reduced oxidative stress and inflammation in UV-induced skin photoaging in rats, promoting collagen recovery and reducing photoaging signs, potentially by inhibiting the PI3K/Akt and NF-κB pathways.

This study found that aging mice with an epidermal deletion of DNA methyltransferase 1 had a reduced number of hair follicles, due to decreased stem cell activation probability.

This study found that topical mesenchymal stem cell conditioned medium improved skin structure by increasing collagen fiber density, hair follicles, and blood vessel number in a mouse model of skin aging.

This review synthesizes research on solar radiation's multifaceted effects on skin and recent advancements in sunscreen technology, including formulation, testing methods, and the use of AI, to inform future sun protection product development.

This study found that gypenosides from Gynostemma pentaphyllum increased procollagen synthesis in vitro and reduced periorbital wrinkles by about 14% in a clinical trial with 24 women.

This paper reviews guidelines discussed at a meeting about research and practice themes, but reports no new research findings.

This review found that cosmeceuticals blend cosmetic and biological skin effects, offering promise in mild dermatoses and photoaging prevention, yet face challenges like regulatory gaps and the need for standardized definitions and pharmacovigilance systems.

In this study, hydrolyzed keratin supplementation using KeraGLO® significantly improved skin parameters such as wrinkle depth, smoothness, moisture, and firmness, as well as hair health, in healthy adult females over a 90-day period at both 500mg and 1000mg doses.

This ex vivo study reported that melatonin significantly improved certain aging biomarkers in aged human skin, including reduced mTORC1 activity, increased fibrillin-1, and enhanced collagen and elastic fiber organization, though other key biomarkers remained unchanged.

This study found that a newly developed keratin active ingredient effectively prevents aging damage in hair by strengthening its structure after exposure to simulated environmental stress.

This study reports that combining ergothioneine, collagen peptides, and sodium hyaluronate improved skin parameters like hydration, elasticity, and wrinkle reduction in Chinese women, while ex vivo data indicated enhanced antioxidant action and structural support, suggesting potential for anti-aging nutricosmetics.

This study in diabetic db/db mice found that treatment with the antihypertensive agents minoxidil or nebivolol stimulated elastogenesis and inhibited elastolysis, leading to restored elastic fibers, reduced aortic stiffening, and normalized blood pressure.

Aging significantly affects the hair and scalp of nonbalding Caucasian women, with changes that differ from male pattern baldness.

This article reviews the potential clinical use of anabolic steroids in treating muscle loss from chronic diseases and aging and highlights both the benefits and risks of these substances in sports.

This review discusses factors affecting hair aging and the current pharmacological treatments for androgenetic alopecia, mentioning topical minoxidil and oral finasteride, but does not present new clinical findings.

This study found that mice with a specific loss of DNA methyltransferase 1 showed uneven epidermal thickness, reduced hair regeneration, and progressive alopecia, emphasizing DNA methylation's role in stem cell homeostasis.

This review discusses cellular senescence in human skin, detailing both beneficial and detrimental effects and suggesting the potential for therapies targeting senescence-related skin disorders, but reports no new clinical results.

In this study, researchers reviewed the literature on the preventive and therapeutic roles of exercise in various skin diseases and assessed whether there are sufficient data to recommend exercise for each condition.

In this study, researchers observed that Finasteride improved cardiac function by enhancing antioxidant levels and reducing oxidative stress in obese and aging rats, though it did not benefit metabolic status and induced insulin resistance in normal diet-fed rats.

UVA exposure slows skin wound healing, but α-klotho can reverse this effect.

This study suggests that applying a botanical extract targeting mechanosensory receptors improved well-being, oxytocin levels, and skin appearance in participants, unlike a placebo.

This study observed that different types of hairline recession increased the perceived facial age of East Asian males, with hair loss type C2 or U2 making those in their 30s appear significantly older.

This study found that TGF-β2 may enhance collagen expression and spheroid formation in human dermal papilla cells, which could improve their hair inductivity and maintenance.