1 citations
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April 2019 in “Acta medica Philippina” This study found that androgenetic alopecia is significantly associated with an increased risk of Metabolic Syndrome, particularly in early-onset male cases and females exhibiting severe AGA.
6 citations
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January 2016 in “International Journal of Trichology” This study found a positive correlation between androgenetic alopecia severity and enlarged prostate size, with more severe cases showing a higher likelihood of prostate enlargement.
24 citations
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January 2013 in “Indian Dermatology Online Journal” This study found that males with androgenetic alopecia had a higher risk of coronary artery disease, with significant differences in several lipid and blood pressure markers compared to controls.
September 2008 in “Fertility and Sterility” This study found that pregnancies with gestational diabetes in a Midwestern U.S. cohort demonstrated elevated androgen levels compared to healthy controls, suggesting a common relationship between impaired glucose tolerance and hyperandrogenemia across diverse ethnic backgrounds.
July 2013 in “The Journal of Clinical Endocrinology & Metabolism” This study showed that androgenetic alopecia independently predicted higher mortality from diabetes and heart disease in both men and women, with increased rates in individuals with moderate or severe AGA.
6 citations
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January 2013 in “Genetics and Molecular Research” This study found that women with androgenetic alopecia demonstrated higher androgen receptor gene expression compared to controls, with a correlation found between higher AR expression and fewer CAG repeats in the AR gene.
October 2023 in “Benha Journal of Applied Sciences” In this study, patients with androgenic alopecia were found to have higher levels of insulin, glucose, and HOMA-IR compared to healthy individuals, suggesting distinct metabolic profiles that may contribute to the condition's development.
May 2023 in “Journal of Cosmetic Dermatology” This study found that AGA patients had higher serum and epidermal irisin levels, which were associated with metabolic syndrome, dyslipidemia, and abnormal carotid intima media thickness, suggesting potential irisin resistance affecting cardiometabolic health.
August 2013 in “Fertility and Sterility” This study found that androgenic alopecia is common in polycystic ovary syndrome, correlates with other hyperandrogenism signs, but not with increased biochemical or metabolic risk compared to PCOS alone.
August 2018 in “Psychological Science” 18 citations
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September 1972 in “British Journal of Pharmacology” In this study on male rats, parachlorophenylalanine treatment induced hypersexual behavior and hair loss linked to increased social interaction but had no effect on brain serotonin when testosterone was used instead.
29 citations
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September 2019 in “Experimental Psychology (formerly Zeitschrift für Experimentelle Psychologie)” This study found that negative social attractiveness ratings for bald men by same-aged women occurred only when individuating information about the target was absent, while the physical attractiveness stereotype remained active at an implicit level.
1 citations
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January 2022 in “Dermatology Research and Practice” This study found that androgenetic alopecia negatively impacts the emotional and social well-being of Polish men, particularly younger individuals, with 66.7% reporting a significant effect on self-esteem.
November 2022 in “Frontiers in Medicine” This study found no direct association between androgenetic alopecia and metabolic syndrome in the Chinese population, though AGA was closely linked with higher systolic blood pressure in men.
1 citations
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January 2010 in “STARS (University of Central Florida)” This study found that men receiving negative appearance-related commentary are more likely to experience negative psychological outcomes, while positive feedback tends to lead to better outcomes despite encouraging appearance-change behaviors.
November 2025 in “Journal of Cosmetic Dermatology” This study reported that young men with early-onset androgenetic alopecia have a higher prevalence of insulin resistance and metabolic syndrome compared to controls, suggesting that AGA may indicate underlying metabolic disturbances.
14 citations
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March 2014 in “Journal of The European Academy of Dermatology and Venereology” This study found that androgenetic alopecia in asymptomatic young men was associated with increased arterial stiffness, as measured by the cardio-ankle vascular index.
5 citations
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February 2019 in “Neuroscience letters” This study found that both declining levels of the neurosteroid THP and increasing levels of estradiol before puberty trigger maximal expression of α4βδ GABAA receptors in the CA1 hippocampus of female mice.
This study found that androgenetic alopecia in Chinese college students is more prevalent in males and is significantly associated with rosacea, with clinic patients experiencing a higher disease burden.
1 citations
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May 2013 in “Journal of the Egyptian Women's Dermatologic Society (Print)” This study found that increased PSA levels in women with hyperandrogenism may serve as a diagnostic marker, comparable to free testosterone levels.
1 citations
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June 2023 in “Psychoneuroendocrinology” This study found that sexual trauma, particularly occurring between ages 5-7, was significantly associated with blunted hair cortisol levels, revealing a potential critical developmental stage affecting HPA axis function. No significant link was observed between cortisol reactivity and other adverse childhood experiences or stressors.
14 citations
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March 2016 in “Journal of Dermatology” This study found that Korean patients with androgenetic alopecia had higher rates of cardiovascular diseases and related risk factors than those without the condition, with variations by severity and type of hair loss.
February 2018 in “PubMed” In a survey of dermatologists, 88% reported an increase in male androgenetic alopecia incidence among men under 30, suggesting possible social or environmental influences on genetic risk factors.
April 2023 in “Nigerian Journal of Clinical Practice” In this study, androgenetic alopecia in Nigerians was associated with dyslipidemia, alcohol intake, and sedentary lifestyle, with severity linked to age, systolic blood pressure, and obesity.
1 citations
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August 2021 in “International Journal of General Medicine” This study found that androgenic alopecia is independently associated with increased coronary artery disease risk and severity of coronary atherosclerosis among Han Chinese men.
67 citations
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January 1997 in “Lancet” This article discusses the causes of hirsutism, identifying increased androgen production and heightened skin sensitivity, and provides no new clinical results.
22 citations
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April 2004 in “Journal of Neurochemistry” In this study, acute restraint stress increased Y1 receptor gene expression in the amygdala and PVN of transgenic mice, but this effect was not due to elevated neuroactive steroid concentrations, indicating a potential ligand-induced mechanism.
42 citations
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April 2009 in “Human Genetics” This study suggests that the AGA risk haplotype in Europeans was driven to high frequency by positive selection, likely associated with a variant in the EDA2R gene.
5 citations
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September 2012 in “The Journal of Urology” This article discusses androgenetic alopecia as a potential early marker for benign prostatic hyperplasia but reports no new clinical findings.
11 citations
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August 2014 in “PubMed” This study found that women with acne had higher rates of hyperandrogenism and obesity, and higher androgen levels and BMI were linked to increased acne severity.