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Perilla frutescens, an East Asian plant, contains 400 bioactive compounds that have various health benefits, including anti-inflammatory, antidepressant, and anticancer effects, and can treat conditions like diabetes, skin allergies, and neurological disorders.

The document concludes that individualized treatments for hair issues are effective, certain hair changes can indicate neurocutaneous diseases, specific lotions improve skin health, laser hair removal works but needs more study on long-term effects, men's cosmetics are diverse, peeling is effective but can have side effects, and facial pigmentation is often due to overactive skin cells.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Testosterone and its metabolites affect brain functions and could help treat neurological disorders.

Finasteride and dutasteride can cause severe, lasting side effects.

Finasteride treatment in rats changed the expression of genes related to psychiatric and neurological functions, and these changes persisted after stopping the drug.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Finasteride helps protect brain in old male rats.

Vegetarians should take B vitamin supplements to avoid health issues.

Azathioprine can help with relapses and disability in NMOSD but has more side effects and needs more research.

Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.

Finasteride may help reduce inappropriate sexual behaviors in dementia patients with prostate issues.

Thiopurines help treat IBD but require genetic testing to avoid side effects.

TNF-alpha inhibitors can cause various immune-related skin issues.

Baricitinib effectively reduces hair loss in severe alopecia areata with mild side effects.

Extracellular vesicles may effectively treat hair loss with minimal side effects.

Memantine may slightly improve memory in people with Down syndrome, but more research is needed.

ALA-PDT is effective and safe for chronic X-ray dermatitis, providing complete or partial remission.

Sirolimus effectively reduces lesions and improves quality of life in Blue Rubber Bleb Nevus Syndrome with manageable side effects.

Post-finasteride syndrome's existence is uncertain; more research needed.

Androgen receptors in the mouse brain may explain cognitive and mood changes in prostate cancer treatment.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

Adults should not consume more than 255 micrograms of selenium per day to avoid risk of hair loss and other side effects.

Eating too much selenium can cause bad breath, hair loss, and nail changes, with harmful effects starting at low daily doses.

Nitrofurantoin may cause sub-acute cutaneous lupus erythematosus.

Microneedle therapy combined with serum effectively increases hair count in people with hair loss, with no side effects.

The document concludes that Passiflora incarnata could help with anxiety, telemedicine might improve heart failure care, screen time for kids has increased, pregnant teens in Brazil are mostly okay with their body image, rare tuberculosis infection can occur after knee surgery, older and severely ill people are more likely to have long COVID-19 symptoms, HPLC might diagnose more diabetes cases, and psychiatrists should be involved in pain management.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Most treatments for spondyloarthritis are safe, but monitoring and careful selection based on patient risks are important.