December 2025 in “Neurobiology of Stress” This study found that individuals with a recent history of suicide attempts exhibited altered DHEA hair levels, suggesting possible dysregulation of the HPA axis as a biopsychosocial feature, and recommends further investigation into hair hormones as potential markers of suicidal crisis and vulnerability.
December 2025 in “Biology” In this study, researchers observed that chronic stress affected wild-derived house mice differently by sex, with females showing less weight gain and distinct behavioral changes, while males exhibited higher hair corticosterone levels, suggesting divergent coping strategies and implications for sex-specific stress assessment protocols.
April 2019 in “Journal of the Endocrine Society” This case study describes a 28-year-old woman with ACTH-independent Cushing's syndrome due to an adrenal adenoma, whose symptoms improved significantly after unilateral adrenalectomy.
May 2018 in “Journal of Saidu Medical College Swat” The study observed that among Afghan women attending a gynecology outpatient department, the majority of those with hirsutism exhibited associated gynecological issues and were primarily categorized as having idiopathic causes or Polycystic Ovarian Disease.
In this study, trilostane was generally effective and well-tolerated for treating canine Cushing's syndrome, though some dogs experienced signs of hypoadrenocorticism, and dose adjustments were necessary over time.
2 citations
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January 2020 in “Clinical Dermatology Review” In this study, idiopathic hirsutism was identified as the most common cause of hirsutism among the patients, followed by polycystic ovarian syndrome.
August 2004 in “Veterinary Dermatology” This study found that hair loss in Chesapeake Bay retrievers may be related to abnormal production of adrenal sex hormones, with further research needed to explore its heritability and treatment options.
1 citations
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February 2017 in “Journal of gynecology and womens health” This review discusses the causes and management of hirsutism, recommending low-dose oral contraceptives with flutamide over cyproterone-containing preparations, but reports no new clinical findings.
61 citations
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March 2003 in “American Journal Of Pathology” Stress can cause hair loss and skin issues by affecting hair growth cycles.
31 citations
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October 2015 in “DOAJ (DOAJ: Directory of Open Access Journals)” This meta-analysis found that the prevalence of PCOS among Iranian women varies by diagnostic criteria, with notable rates of associated complications like hirsutism, acne, and menstrual disorders.
11 citations
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May 2024 in “Reproductive Biology and Endocrinology” In this study, researchers found that human ovaries at different life stages biosynthesize both canonical and non-canonical steroid hormones, with fetal ovaries showing higher enzyme activity related to estradiol and testosterone conversion compared to adult tissues.
11 citations
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April 2023 in “Skin Health and Disease” This review discusses the interplay between dermatology and psychology in psychodermatology, highlighting the impact of neuroendocrine stress pathways on skin diseases and the importance of considering skin of color.
10 citations
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March 2024 in “Endocrine Reviews” In this retrospective review, the author discusses key discoveries in understanding androgen excess disorders like PCOS, focusing on genetic and molecular insights gained from 1965 to 2015.
3 citations
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May 2025 in “Clinical Endocrinology” Evaluate and manage androgen excess in women with a systematic approach, considering both physical and psychological impacts.
2 citations
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July 2017 in “Oman medical journal” This report describes a rare case of a malignant feminizing adrenocortical tumor in a 44-year-old man who lacked the typical presentation of gynecomastia and died four months after diagnosis despite treatment.
January 2025 in “Journal of Clinical Medicine” This study found that among Portuguese women with hirsutism, polycystic ovary syndrome was the most prevalent cause, associated with distinct hormonal features and higher BMI compared to controls.
May 2023 in “IntechOpen eBooks” This review outlines the role of testosterone in male sexual development and its therapeutic use for male hypogonadism, covering its biosynthesis, secretion, metabolism, and various biological actions, but does not report specific study results.
November 2022 in “The Journal of Clinical Endocrinology and Metabolism” This review discusses the causes and recommended clinical investigations for postmenopausal hyperandrogenism, highlighting the role of androgen excess in symptoms like hirsutism and its association with metabolic disorders.
90 citations
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May 2019 in “Drugs” Long-term use of azole antifungals can cause hair loss, hormonal imbalances, and severe skin reactions.
3 citations
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May 2012 in “BMC Endocrine Disorders” This article presents a unique case of post-partum panhypopituitarism and autoimmune conditions in a 37-year-old woman from Africa, emphasizing the need for early diagnosis and treatment to improve outcomes in similar settings.
1 citations
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May 2022 in “Reproductive Endocrinology” This review discusses the complexities of diagnosing and managing hyperandrogenism in women, emphasizing the need for careful evaluation of both clinical signs and biochemical markers without reporting new clinical results.
January 2007 in “Annals of The Royal College of Surgeons of England” This case report describes a 64-year-old woman with male pattern hair loss and elevated testosterone levels, who was diagnosed with an androgen-secreting adrenal tumor and successfully treated with laparoscopic adrenalectomy.
January 2014 in “Theriogenology” This study found that blocking neurosteroid synthesis in the brain of pregnant sheep elevated HPA axis activity, suggesting neurosteroids play a vital role in moderating stress response.
50 citations
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July 2018 in “Psychoneuroendocrinology” In this study, researchers found that tritiated cortisol was incorporated into the hair of rhesus monkeys primarily as cortisol and cortisone, as well as other metabolites, after systemic administration.
2 citations
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November 2015 in “Endocrinology, Diabetes & Metabolism Case Reports” This case report describes a 57-year-old man's late diagnosis of X-linked adrenoleukodystrophy, highlighting the need to consider this condition in patients with non-autoimmune primary adrenal insufficiency and neurological issues.
October 2024 in “Journal of the Endocrine Society” This case report details a diagnostic challenge in a postmenopausal woman with severe hyperandrogenism where distinguishing between adrenal and ovarian causes was complicated by elevated 17-OH Progesterone and asymmetric ovarian enlargement; pending surgical pathology is expected to guide further management.
February 2022 in “Endocrine connections” This review summarizes existing research on how various endocrinopathies, including reproductive disorders and thyroid conditions, can affect vocal parameters, and reports no new clinical findings.
1 citations
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November 2021 in “Biomedicines” This review elaborates on the concept of cutaneous mosaicism and its link to acneiform conditions, but it reports no new clinical results.
32 citations
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June 2019 in “Frontiers in Endocrinology” This review discusses the overlapping clinical features and diagnostic challenges of non-classic adrenal hyperplasia and polycystic ovary syndrome without presenting original research findings.
23 citations
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January 2016 in “Brazilian Journal of Psychiatry” This study observed that drug-naïve first-episode psychosis patients had higher hair cortisol concentrations than healthy controls, and these concentrations correlated with the severity of psychopathology.