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Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Fat cells help recruit healing cells and build skin structure during wound healing.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Allergic reactions to blood thinners are rare but can be serious, requiring careful testing and alternative treatments.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

Combining liraglutide and metformin helps obese women with PCOS who didn't lose weight on metformin alone to lose more weight.

Platelet-rich plasma may help with hair growth and skin quality but more research is needed to confirm its effectiveness.

Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.

Women with type 1 diabetes often have polycystic ovary syndrome and excess male hormones, which are frequently undiagnosed.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

Dermal Papilla cells are a promising tool for evaluating hair growth treatments.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Dermal exosomes with miR-218-5p boost hair growth by controlling β-catenin signaling.

Microneedle technology has improved drug delivery and patient comfort but needs more research for broader use.

Condensed nanofat with fat grafts effectively improves atrophic facial scars.

The new micelle formulation delivers acne treatment more effectively and safely than current gels.