research Syndecan-1 Is Required to Maintain Intradermal Fat and Prevent Cold Stress
Syndecan-1 is essential for maintaining skin fat and preventing cold stress.
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research Smart Microneedles for Therapy and Diagnosis
Microneedle technology has advanced for painless drug delivery and sensitive detection but faces a gap between experimental use and clinical needs.
research Degeneration in Dermatopathology
The document concludes that understanding tissue degeneration is crucial for diagnosing skin lesions.
research The JAK/STAT Signaling Pathway: From Bench to Clinic
The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
research The Effects of Lower vs Higher Cell Number of Platelet-Rich Plasma on Hair Density and Diameter in Androgenetic Alopecia: A Randomized, Double-Blinded, Placebo, Parallel-Group Half-Scalp IRB-Approved Study
Higher cell number PRP improves hair density and diameter more than lower cell number PRP.
research Systematic Review of Platelet-Rich Plasma in Medical and Surgical Specialties: Quality, Evaluation, Evidence, and Enforcement
PRP shows promise but lacks consistent evidence and regulation.
research Pharmacotherapy for Keloids and Hypertrophic Scars
Combination pharmacotherapy is generally more effective for treating keloids and hypertrophic scars.
research Hair Regeneration Using Microneedle-Assisted Human Basic Fibroblast Growth Factor
Microneedle-assisted therapy with human basic fibroblast growth factor significantly regrew hair in patients with hair loss.
research Hypoxia Enhances the Hair Growth-Promoting Effects of Embryonic Stem Cell-Derived Mesenchymal Stem Cells Via NADPH Oxidase 4
Low oxygen conditions improve how well certain stem cells from embryos can make hair grow longer and faster.
research Resident Stem Cells in Skin
Skin stem cells can help improve skin repair and regeneration.
research Therapeutic Potential of Endogenous Stem Cells and Cellular Factors for Scar-Free Skin Regeneration
Using skin stem cells and certain molecules might lead to scar-free skin healing.
research Overexpression of Hypoxia-Inducible Factor-1α in Hidradenitis Suppurativa: The Link Between Deviated Immunity and Metabolism
Increased HIF-1α is linked to the inflammation and severity of hidradenitis suppurativa, suggesting treatments that lower HIF-1α could help.
research Melatonin Membrane Receptors in Peripheral Tissues: Distribution and Functions
Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.
research Fibroblast State Switching Orchestrates Dermal Maturation and Wound Healing
Fibroblast state switching is crucial for skin healing and development.
research Engineered Hair Follicle Mesenchymal Stem Cells Overexpressing Controlled-Release Insulin Reverse Hyperglycemia in Mice with Type 1 Diabetes
Genetically modified stem cells from human hair follicles can lower blood sugar and increase survival in diabetic mice.
research Proliferative and Non-Proliferative Lesions of the Rat and Mouse Integument
The project created a standardized system for classifying skin lesions in lab rats and mice.
research Contents
Biologicals are increasingly used in medicine and cosmetics, especially for skin and hair treatments, but more research is needed.
research The Role of Local and Systemic Leptin in Androgenetic Alopecia
Higher leptin levels link to hair loss.
research Use of Ultra-Fast One-Step CK5 IHC for Identifying BCC and SCC During Mohs Surgery
A new one-step test can quickly identify skin cancer during surgery.
research Structural Changes in Human Skin After Topical Application of Glucocorticoids Assessed by In Vivo Imaging Technologies
Topical glucocorticoids thin the skin and change collagen structure.
research Down-Regulatory Role of Cholecystokinin on Psoriatic Epidermal Inflammation
Cholecystokinin may help reduce skin inflammation in psoriasis.
research A Novel Small Compound HPH-15 Antagonizes TGF-β/Smad Signaling and Ameliorates Experimental Skin Fibrosis
HPH-15, a new compound, effectively reduces skin fibrosis in experiments without causing harm.
research Deep Phenotyping of Patients with Xeroderma Pigmentosum and Trichothiodystrophy
Deep phenotyping helps distinguish between xeroderma pigmentosum and trichothiodystrophy, aiding in diagnosis and treatment.
research Ethnopharmacological Significance of Eclipta Alba (L.) Hassk. (Asteraceae)
Eclipta alba has many health benefits and contains compounds with potential for drug development.
research The 'Bald' Phenotype (Androgenetic Alopecia) Is Caused by the High Glycemic, High Cholesterol, and Low Mineral 'Western Diet'
Western diet may cause male pattern baldness; low glycemic diet with magnesium could help.
research Secreted Frizzled-Related Protein 4 Inhibits the Regeneration of Hair Follicles
A protein called sFRP4 can slow down hair regrowth.
research Exploring the Role of Stem Cells in Cutaneous Wound Healing
Stem cells are crucial for wound healing and understanding their role could lead to new treatments, but more research is needed to answer unresolved questions.
research Emerging Nonmetabolic Functions of Skin Fat
Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.
research Hedgehog Signaling Reprograms Hair Follicle Niche Fibroblasts to a Hyper-Activated State
Overactivating Hedgehog signaling makes hair follicle cells in mice grow hair faster and create more follicles.
research Reprogramming Adult Dermis to a Neonatal State Through Epidermal Activation of Beta-Catenin
Activating a protein called β-catenin in adult skin can make it behave like young skin, potentially helping with skin aging and hair loss.