43 citations
,
December 2013 in “Seminars in Cell & Developmental Biology” This mini-review discusses human hair follicle development and summarizes genetic disorders linked to abnormalities in hair follicle morphogenesis, structure, or regeneration, but reports no new experimental results.
22 citations
,
April 2012 in “The American journal of pathology” This study found that the loss of Msx2 in knockout mice led to phenotypes similar to Peters anomaly and microphthalmia, suggesting that MSX2 plays a critical role in anterior segment development of the eye.
20 citations
,
December 2020 in “Frontiers in Immunology” This study found that certain T cell-associated genes were upregulated in dogs with Vogt-Koyanagi-Harada syndrome and vitiligo, suggesting a shared immunopathogenesis with humans.
20 citations
,
February 1968 in “Journal of Histochemistry & Cytochemistry” This study reports that citrulline, uniquely found in the inner root sheath of hair follicles, can be specifically detected with the carbamido diacetyl reaction, resulting in a bright orange color.
19 citations
,
October 2007 in “Wound Repair and Regeneration” This paper reviews signaling influences and niches of epidermal stem cells and compares various types, but does not present new experimental findings.
14 citations
,
May 2022 in “Stem cell reports” This study reported that human induced pluripotent stem cell-derived skin organoids, used to model epidermolysis bullosa, have an epidermal-dermal junction largely lacking type VII collagen, which is important for skin structure.
10 citations
,
May 2021 in “International Journal of Cosmetic Science” This study found that split-head paired design trials are as effective as whole-head parallel design trials in differentiating anti-dandruff shampoos through scalp flaking measurements, but are more efficient and cost-effective, requiring fewer participants to achieve similar results.
6 citations
,
May 2013 in “PloS one” This study found that the Foxn1(-/-) nude phenotype significantly influences epithelial progeny in skin, with notable changes in stem cell niches not achievable in other models.
3 citations
,
July 2022 in “Stem Cell Research & Therapy” This study found that knocking out the integrin β1 subunit in induced pluripotent stem cells enhanced their migration and improved their wound-healing effects in a mouse model.
January 2026 in “Preprints.org” This review explores current knowledge on fibroblast lineage specification and its impact on scar-free wound healing, noting that early fetal skin fibroblasts support regeneration, while later developmental shifts lead to fibrosis, highlighting potential strategies to reprogram adult fibroblasts for regenerative repair.
August 2025 in “Frontiers in Pharmacology” In this study, PA-011, a traditional Chinese medicine extract, was shown to improve hair growth in alopecia areata model mice by reducing skin inflammation and altering skin microbiota, indicating its potential therapeutic role for this condition.
October 2024 in “International Journal of Pharmaceutics” This study aimed to develop a new transdermal patch for treating androgenetic alopecia using finasteride, combined with chemical permeation enhancers to improve drug delivery through the skin, but results of pharmacokinetics and pharmacodynamics evaluations are not reported.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that STRIP1 and the STRIPAK complex play a key role in regulating F-actin and cell-cell junctions, which are essential for maintaining the epidermal barrier in mouse skin.
October 2021 in “QJM: An International Journal of Medicine” This study found increased H2O2 levels and decreased E-cadherin levels in vitiligo patients compared to controls, suggesting oxidative stress and compromised cell adhesion may impact the pigmentary system in vitiligo-affected skin.
This study found that PRL-1-overexpressing PD-MSCs reduced adipogenesis in orbital fibroblasts from Graves' ophthalmopathy patients by secreting IGFBPs and modulating the FAK pathway.
August 2018 in “Journal of The American Academy of Dermatology” Regular follow-up visits, especially with dermatologists, can lower death rates for melanoma patients, with socioeconomic factors also affecting outcomes.
February 2010 in “Journal of the American Academy of Dermatology” Activating cAMP and ATP improves hair growth and strength.
September 2008 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Loss of Dsc3 function in the epidermis impaired cell adhesion, leading to blistering and hair loss, which suggests a potential cause of PV-like skin diseases according to this study.
5 citations
,
December 2024 in “Patient Preference and Adherence” In this study, despite most patients recognizing alopecia areata as serious and adhering to treatment, psychological well-being remained adversely affected by the disease, highlighting the need for larger studies to better address these psychological impacts.
3 citations
,
February 2024 in “Patient Preference and Adherence” In this study, the authors suggest that patient safety with isotretinoin in Palestine can be improved by adapting pharmacy and medical practice protocols to better educate patients and ensure adherence to safety monitoring and laboratory ordering.
April 2011 in “Journal of physiology and pharmacology : an official journal of the Polish Physiological Society” This study found that drug adherence rates in men with benign prostatic hyperplasia were low, decreasing with longer treatment duration, and were higher in patients with more severe symptoms.
This study observed that adherence to finasteride treatment in patients with benign prostatic hyperplasia at a clinic in Tepic Nayarit had not been previously evaluated in Mexico.
41 citations
,
May 2012 in “Advanced Healthcare Materials” This study found that human hair keratin coatings enhanced adhesion and proliferation of L929 mouse fibroblasts compared to uncoated and collagen type 1 surfaces, suggesting keratin's potential as a surface coating for cell cultures.
26 citations
,
May 2011 in “Tissue Engineering Part A” This study found that mouse embryoid bodies adhered quickly and differentiated efficiently into cardiomyocytes on negatively charged poly(sodium p-styrene sulfonate) hydrogels, similar to their behavior on gelatin-coated polystyrene.
3 citations
,
November 2025 in “Annals of Medicine” This study found that higher adherence to healthy dietary patterns such as DASH, AHEI, and MED significantly reduced all-cause mortality in hypertensive patients, with the DASH diet particularly lowering cardiovascular mortality, highlighting diet's role in hypertension management.
April 2020 in “Rheumatology” This study found significant but small variations in glucocorticoid adherence among patients with giant cell arteritis, mainly due to medical advice rather than patient factors.
99 citations
,
January 2004 in “Journal of Biological Chemistry” This study found that methylprednisolone can block IgG-induced keratinocyte detachment in an animal model of pemphigus vulgaris, potentially by increasing the synthesis and modifying adhesion molecules.
June 2023 in “Acta Scientifci Nutritional Health” This study found that children with celiac disease who adhered to a gluten-free diet experienced significant improvements in height, weight, and symptoms like diarrhea and abdominal pain, although cases of abdominal distention increased.
July 2021 in “Clinical Medicine” This abstract does not report research results but acknowledges feedback concerning adherence to inclusion criteria from a prior study on the Ottawa rule by Perry et al., as shared in their CT-based clinical research.
January 2008 in “Zhongguo zuzhi gongcheng yanjiu yu linchuang kangfu” This study found that selecting human vaginal mucosa stem cells by adhesion to type Ⅳ collagen for 20 minutes and culturing them with feeder layer and epidermal total culture media was most effective in maintaining their characteristics.