Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that testosterone and dihydrotestosterone significantly decreased the proliferation of papilla cells compared to dermal fibroblasts and outer root sheath keratinocytes in cultured hair follicle cells.

This article discusses hormonal mechanisms underlying androgenetic alopecia but does not report any new findings; it reviews the roles of dihydrotestosterone and available FDA-approved treatments.

This case study reported that a 13-year-old cat with paraneoplastic alopecia due to an intraabdominal apocrine adenocarcinoma exhibited ventrally distributed alopecia and shiny skin, with necropsy showing telogenisation and miniaturisation of the hair follicles.

This study found that activating β-catenin signaling in embryonic epidermis promoted hair follicle characteristics at the expense of normal epidermal differentiation, leading to early pigmentation and innervation.

This study demonstrated that α-phellandrene promotes dermal papilla cell proliferation through a cAMP-mediated pathway and upregulates VEGF expression, suggesting its potential use in hair loss prevention.

This article reviews the clinicopathologic features of short anagen syndrome in a child and suggests diagnostic methods like clinical examination and scalp hair growth rate measurement, without reporting new clinical results.

This research found evidence of inflammatory involvement in androgenetic alopecia, with higher deposition of certain immune components in the scalp of affected patients compared to those without baldness.

This case report describes a post-menopausal woman with severe hirsutism whose high testosterone levels decreased after gonadotropin suppression, indicating residual hormone-producing tissue responsive to gonadotropins.

TGF-β1 from dermal papilla cells suppresses hair growth, and targeting it may help treat androgenetic alopecia.

This review explores the key factors influencing hair growth implicated in androgenetic alopecia and reports no new clinical findings.

This article discusses the structures surrounding hair follicles and introduces aspects like follicle groups and the dermal sheath, but it reports no new research findings.

This study found that adolescents with androgenetic alopecia showed distinct hormonal profiles between boys and girls, with concurrent metabolic dysfunction present in both sexes, highlighting the need for sex-specific diagnosis and management approaches.

This study found that persistent activation of Wnt signaling in mouse models leads to cyst formation in hair follicles, resembling acne, and that these cysts can be partially reduced by certain acne treatments.

This review explores how androgens and growth hormone influence the development of terminal hairs and sebaceous glands, attributing variability in hirsutism and acne to differing genetic sensitivities to androgens, but reports no new experimental data.

This study found that Blimp1+ cells from mice can generate sebaceous gland organoids in vitro, which mimic natural gland traits and may aid in studying acne vulgaris.

In this study, researchers found that topical apigenin promoted hair growth in a testosterone-induced alopecia mouse model, with effects comparable to minoxidil, suggesting a potential treatment approach for androgenetic alopecia through the Wnt signaling pathway.

This case report found that a dog's progressive alopecia and prostatitis were caused by ingesting a transdermal estradiol cream, emphasizing the need to identify exogenous estrogen sources during evaluation.

Telogen effluvium is a type of temporary hair loss.

This article examines the terminal to vellus transition in androgenetic alopecia through cellular and developmental mechanisms, discussing challenges and knowledge gaps without presenting new clinical findings.

This study reports that during late embryogenesis and early postnatal development, K79-expressing keratinocytes change and die independently of sebaceous glands to form the hair follicle opening, potentially influencing conditions like ingrown hairs or acne.

This report describes two children with congenital hypotrichosis and found their short hair is due to a shortened anagen phase, with the condition resolving spontaneously during puberty.

The researchers observed that overexpression of Wnt10b in a mouse model can induce hair follicle regeneration by switching follicles from the resting phase to the growth phase via the Wnt-β-catenin signaling pathway.

A Saudi girl was diagnosed with Loose Anagen Hair Syndrome, a rare condition causing easy hair loss without scarring.

This study suggests that new cells are incorporated into the dermal papilla during the early anagen phase of the hair cycle, which may influence hair growth consistency and follicle size changes.

ACTH promotes hair growth in mink, but α-MSH does not.

This case study reports a rare instance of an estradiol-secreting adrenocortical carcinoma in a 58-year-old male, causing feminization and Marie-Antoinette syndrome, with potential paraneoplastic aortitis.

In this study using transgenic mice, activating P-catenin signaling induced new hair follicle formation and maintained follicle tumors, with implications for understanding skin homeostasis.

This case study reported that prolonged use of the cancer drug Erlotinib in a postmenopausal woman was associated with trichomegaly and hypertrichosis, highlighting the importance of considering medication history in such cases.