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Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

The document recommends using both clinical evaluation and various measurement methods to assess skin greasiness, considering factors like temperature and hormones.

Minoxidil increases blood flow in balding scalps, possibly reversing hair loss.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

Coal tar shampoos, salicylic acid, and topical corticosteroids are effective for scalp psoriasis, with Vitamin D3 analogues also showing benefits; severe cases may require stronger medication with more risks.

Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Minoxidil helps heart function but doesn't improve exercise ability and may cause complications.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

Grafted rodent and human cells can regenerate hair follicles, but efficiency decreases with age.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

Phospholipase A2 is necessary for the correct placement of PIN proteins in plant roots, affecting root growth.

Treatments for melanin disorders exist, but more effective options needed.

Minoxidil boosts hair growth by activating PGHS-1.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Hirsutism is a strong sign of high male hormones and metabolic problems in women with PCOS, but acne and hair loss are not.

PHBV nanofiber matrices help wounds heal faster when used with hair follicle cells.

Minoxidil slows fibroblast growth and collagen production, potentially treating keloids, hypertrophic scars, and connective tissue disorders.

Using minoxidil on dogs can cause serious cardiovascular damage, including arterial injury and hemorrhagic lesions.

Obese women with PCOS show a male-like pattern in certain fat tissue gene expressions.

Key genes are crucial for Drosophila wing development and could be insecticide targets.

Minoxidil, propranolol, and furosemide effectively control severe hypertension, but may cause sodium retention.

Edible seeds from the Cucurbitaceae family like pumpkin and watermelon seeds are nutritious and may have health benefits, but eating too much can cause side effects.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.