Anti-Androgens in Gynecological Practice

    September 1988 in “ Baillière's clinical obstetrics and gynaecology ”
    Michael J. Reed, Stephen Franks
    Studysummary This article discusses the mechanisms of hirsutism and acne in women, highlighting cyproterone acetate with ethinyloestradiol as an effective anti-androgen therapy in the UK, but it reports no new clinical findings.
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    Research cited in this study 16

    1. Side Effects of Spironolactone Therapy in the Hirsute Woman ˜The œJournal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism · 1988
    2. A Comparative Study of Aldactone and Diane in the Treatment of Hirsutism Journal of steroid biochemistry/Journal of Steroid Biochemistry · 1987
    3. Treatment of Hirsutism and Acne with Cyproterone Acetate Clinics in Endocrinology and Metabolism · 1986
    4. Cyproterone Acetate as Initial Treatment and Maintenance Therapy for Hirsutism European journal of endocrinology · 1985
    5. Spironolactone in Combination Drug Therapy for Unresponsive Hirsutism Fertility and sterility · 1985
    6. The Effects of Two Doses of Spironolactone on Serum Androgens and Anagen Hair in Hirsute Women Fertility and sterility · 1985
    7. Female Hirsutism: Pathophysiological Considerations and Therapeutic Implications Endocrine reviews · 1984
    8. Dihydrotestosterone Stimulates 5α-Reductase Activity in Pubic Skin Fibroblasts ˜The œJournal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism · 1983
    9. 3 Alpha, 17 Beta-Androstanediol Glucuronide in Plasma: A Marker of Androgen Action in Idiopathic Hirsutism ˜The œJournal of clinical investigation/˜The œjournal of clinical investigation · 1982
    10. A Novel Use of Spironolactone: Treatment of Hirsutism ˜The œJournal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism · 1980
    11. New Therapeutic Approach to the Hirsute Patient Fertility and sterility · 1979
    12. Interaction of Spironolactone with Rat Skin Androgen Receptor Canadian journal of biochemistry · 1979
    13. Use of Cyproterone Acetate in the Treatment of Acne, Hirsutism, and Virilism Journal of Steroid Biochemistry · 1975
    14. The Evaluation of the Role of Androgens in Hirsutism and the Use of a New Anti-Androgen Cyproterone Acetate for Therapy ˜The œJournal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism · 1974
    15. Biological Activity of Antiandrogens British journal of dermatology/British journal of dermatology, Supplement · 1970
    16. The Effect of Anti-Androgens on the Response of Rat Preputial Glands to Testosterone ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1964