75 citations
,
August 2018 in “Plant physiology” In this study, researchers found that increased hydrogen sulfide levels in Arabidopsis disrupted actin dynamics through S-sulfhydration, leading to the depolymerization of actin filaments and inhibited root hair growth.
56 citations
,
December 2011 in “The Plant Journal” AGD1 is important for root hair development in Arabidopsis, working with phosphoinositide signaling and the actin cytoskeleton.
12 citations
,
December 2023 in “Plant Communications” This study found that long-term exposure to high pH extends root hair elongation by altering actin filament arrangements and vesicle trafficking, but disrupting ADF8/11 function shortens root hairs by affecting these processes.
110 citations
,
April 2009 in “Cell Motility and the Cytoskeleton” This review discusses the intracellular activity of β-thymosins and their role in modulating the actin cytoskeleton, but it reports no new experimental results.
89 citations
,
June 2012 in “Anais Brasileiros de Dermatologia” This review compiles epidemiological data on actinic keratoses and suggests promoting strategies like early diagnosis and photoprotection to prevent progression to skin cancer, but it reports no new clinical findings.
32 citations
,
December 2003 in “Planta” This study found that hypaphorine alters cytoskeletal organization in Eucalyptus globulus root hairs, contributing to reduced root hair elongation by possibly disrupting vesicle delivery needed for growth.
27 citations
,
December 2014 in “Current problems in dermatology” This book reviews actinic keratosis from a multidisciplinary perspective, covering topics such as epidemiology, immunology, and clinical manifestations, but reports no new research results.
13 citations
,
February 1999 in “International Journal of Cosmetic Science” This study observed a higher incidence of telogen effluvium from July to October, suggesting a summer-related effect in populations above the Tropic of Cancer, possibly influenced by ultraviolet light.
10 citations
,
May 2023 in “Journal of Investigative Dermatology” In this study, 21.1% of participants had actinic keratoses, with higher prevalence in men, and certain genetic and photoaging factors were positively associated with AK, though smoking was linked to reduced risk.
10 citations
,
August 2003 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” This case report documents a 30-year-old man's presentation with actinic superficial folliculitis and characterizes the inflammatory infiltrate, supporting the classification of this condition as a distinct disease entity.
9 citations
,
July 2017 in “Dermatologic Therapy” Two elderly men developed scalp inflammation after using a gel for skin lesions, which healed with treatment except for some permanent hair loss.
9 citations
,
September 2009 in “Journal of Cutaneous Medicine and Surgery” This study reports cases of androgenetic alopecia patients with depigmented macules on sun-exposed scalp areas, suggesting potential ultraviolet-induced scalp leukoderma not covered in existing dermatology texts.
8 citations
,
July 2024 in “Scientific Reports” This study reported that administering salicylates to wounds in adult mice promoted wound healing patterns similar to embryonic wounds, enabling complete wound regeneration and reduced scarring by activating AMPK and subsequent signaling pathways.
6 citations
,
November 2018 in “Photodiagnosis and Photodynamic Therapy” This study found that using a wearable low-level light therapy device for photodynamic therapy significantly reduced actinic keratosis lesions and improved quality of life in patients with AK of the scalp.
6 citations
,
January 2015 in “Biochemical Society Transactions” This review discusses the role of Ysc84/SH3yl1 proteins in linking actin regulation to membrane morphology changes but reports no new experimental results.
5 citations
,
May 2006 in “Dermatologic Surgery” This study found that a PEEP of 10 mbar for 2 hours did not adversely affect liver function or gastric mucosal perfusion in patients after cardiac surgery, as long as cardiac output was maintained.
4 citations
,
May 2020 in “PLOS ONE” This study found that ingenol mebutate treatment led to gene expression changes in actinic keratoses, with complete lesion clearance in 40% of patients and identified genetic markers potentially predicting treatment response.
3 citations
,
April 2017 in “Journal of Investigative Dermatology” This study found that dermoscopy is valuable for diagnosing facial actinic keratosis in Chinese patients, with specific patterns like red pseudonetwork and follicular plugs suggesting its utility in differential diagnosis.
2 citations
,
May 2022 in “Acta dermato-venereologica” In this study, patients with frontal fibrosing alopecia showed more actinic damage than control subjects, suggesting sunscreen use by these patients may be a consequence rather than a cause of the condition.
1 citations
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September 2025 in “PLoS ONE” This study observed that in mouse fetuses, reticular contraction by actomyosin is involved in dermal regeneration, and differences in actin and α-SMA localization may determine the switch between regeneration and scar formation, suggesting potential insights for wound regeneration therapy.
1 citations
,
April 2016 in “Journal of The American Academy of Dermatology” A man developed a rare skin condition and drug-induced lupus, highlighting the need for biopsy in diagnosing skin issues caused by sunlight.
June 2026 in “British Journal of Dermatology” This case study suggests that intense inflammation after photodynamic therapy may trigger or worsen fibrosing alopecia in susceptible individuals.
In this case study, the researchers observed that a dermocosmetic formulation with encapsulated retinol led to complete regression of a chronic actinic keratosis lesion on the scalp, suggesting it may be a promising treatment approach.
January 2025 in “ARC Journal of Clinical Case Reports” This case report suggests that using encapsulated retinol in polylysine may effectively treat actinic keratosis with minimal irritation, potentially providing a safer alternative for frequent use.
August 2024 in “International Journal of Molecular Sciences” This study found that root hairs of wild-type Arabidopsis grow faster and longer under low potassium stress, with changes in actin filament dynamics and specific regulation by the actin bundling proteins VLN1 and VLN4.
April 2024 in “Dermatovenerologiâ, kosmetologiâ” This material provides comprehensive information about actinic keratosis, highlighting its potential outcomes, risk factors, clinical features, diagnosis, and treatment considerations for medical specialists.
April 2024 in “Dermatovenerologiâ, kosmetologiâ” This study provides a comprehensive overview of actinic keratosis, highlighting its potential to progress to squamous cell carcinoma and noting that routine treatment poses a significant burden on healthcare providers.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that HPV8-induced actinic keratoses may mechanistically involve Lrig1+ hair follicle keratinocyte stem cells, with the E6 gene promoting downstream STAT3 activity in a mouse model.
July 2017 in “Chinese Journal of Dermatology” This study concluded that a combination of three specific dermoscopy features provides the highest diagnostic value for distinguishing actinic keratosis from other facial lesions.
April 2017 in “Journal of Investigative Dermatology” This study found that a single dose of TRP significantly reduced the number of UV-B-induced actinic keratosis lesions in a mouse model and was associated with improved skin histology and minimal side effects.