April 2016 in “Journal of The American Academy of Dermatology” Daylight photodynamic therapy is effective and well-tolerated for treating actinic keratoses with minimal side effects.
May 2006 in “Dermatologic Surgery” This article contains only correspondence information and acknowledges contributions but reports no new research results.
December 2015 in “Journal of skin and stem cell” This study reports three cases where patients treated with topical 3% diclofenac gel for scalp actinic keratosis also experienced hair growth in androgenetic alopecia-affected areas.
40 citations
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July 2011 in “The journal of clinical hypertension” This article reviews the use of hydralazine, minoxidil, and sodium nitroprusside in managing hypertension and hypertensive crises, noting specific indications, adverse effects, and the adjunctive therapies needed to mitigate side effects.
37 citations
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November 2007 in “Journal of Biological Chemistry” This study found that increased intracellular expression of thymosin β4 is necessary and sufficient to induce PAI-1 gene expression in endothelial cells, potentially mediated through Ku80 as a novel receptor.
25 citations
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May 2006 in “Annals of Botany” This study suggests that a tip-focused gradient of intracellular G-actin concentration at the apex is crucial for root hair growth, and maintaining this gradient requires high calcium levels at the root hair tips.
12 citations
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December 2022 in “Current Protein and Peptide Science” This review discusses the molecular mechanisms and clinical applications of thymosin β4, highlighting its potential benefits for inflammation, wound healing, tumor metastasis, and other medical conditions but reports no new experimental results.
10 citations
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April 1964 in “Journal of the American Geriatrics Society” This article reviews triamcinolone acetonide as an intramuscular long-acting steroid therapy for dermatologic disorders but reports no new clinical results.
6 citations
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March 2021 in “International Journal of Pharmaceutics” This study reported that a subcutaneous injection formulation using PLGA microspheres to release finasteride stably achieved sustained monthly drug delivery without burst release in beagle dogs, with a dose of 16.8 mg identified as optimal for potential first-in-human trials.
5 citations
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December 2022 in “Toxins” This review discusses the structural properties, pharmacological effects, and clinical applications of neurotoxins on synapses, reporting no new experimental results.
4 citations
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November 2020 in “BMC Dermatology” This study identified 374 eQTLs in scalp hair follicles associated with genes involved in metabolic, mitotic, immune processes, and responses to steroid hormones, contributing insights into genetic variation and hair traits.
3 citations
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August 2012 in “Nature Cell Biology” This study found that the Wnt-β-catenin pathway directly promotes TERT expression in both stem and cancer cells, highlighting a mechanistic link between tumorigenesis and pluripotency.
1 citations
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August 2023 in “Advanced Drug Delivery Reviews” This review discusses various microneedle technologies for long-acting drug delivery, highlighting design considerations and challenges in bringing these minimally invasive devices to market, but it reports no new clinical results.
July 2026 in “Our Dermatology Online” This study observed a significant rise and fall in black hair dye dermatitis cases over six years, primarily affecting middle-aged men, with most cases presenting as chronic pigmented lichenoid photodermatitis.
February 2026 in “Clinical Cosmetic and Investigational Dermatology” In this case report, a 67-year-old Thai woman exhibited isolated cheilitis due to actinic prurigo—an unusual presentation in Asian patients—successfully treated with topical hydrocortisone and sun protection, highlighting the need to consider actinic prurigo in chronic lip lesion diagnoses even with normal phototesting results.
July 2024 in “The Egyptian Journal of Hospital Medicine” In this study of Egyptian patients on hepatitis C treatment, 34% experienced skin-related side effects from sofosbuvir and daclatasvir, such as itching and hyperpigmentation, but most reactions were mild and reversible without needing to stop therapy.
This study demonstrated that the IVL-DrugFluidic® platform is effective for mass-producing finasteride-loaded polymeric microspheres for long-acting injectables, maintaining stable drug release without an initial burst for a month.
December 2022 in “International Journal of Pharmaceutics” This study estimated the starting dose range for a finasteride long-acting injectable formulation in humans, suggesting that 16.80 mg may be the optimal starting dose.
May 2022 in “The FASEB Journal” This experimental study suggests that finasteride may reduce Lymphocyte Specific Protein 1 gene expression through methylation in human Leydig cells, potentially offering a pathway for treating Neutrophil Actin Dysfunction.
November 2018 in “Biomedical Journal of Scientific and Technical Research” This article discusses the use of PRP and long-acting PRP for treating Female Pattern Hair Loss, emphasizing their potential benefits, but reports no new clinical results.
May 2016 in “Hair transplant forum international” 82 citations
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January 2011 in “New Phytologist” This study demonstrated that AtVLN4 plays a role in root hair growth by regulating actin organization in a calcium-dependent manner.
62 citations
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March 2017 in “Journal of Investigative Dermatology” Mutations in the ACTB gene cause Becker’s nevi and may lead to muscle issues in Becker’s nevus syndrome.
12 citations
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April 2023 in “Molecular Pharmaceutics” This study demonstrated that a microarray patch can deliver antibodies in a controlled and prolonged manner, maintaining their functionality after manufacturing and heat exposure, with successful pharmacokinetic proof-of-concept in rats.
6 citations
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September 1988 in “Drug intelligence & clinical pharmacy” This report documents a case of dermatological toxicity associated with chronic minoxidil therapy, highlighting the emergence of a severe rash after three years of use, which recurred upon inadvertent rechallenge.
3 citations
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August 2024 in “The Journal of Cell Biology” This study demonstrated that in live rodents, actin filaments adjust their structure to facilitate membrane transfer between cellular compartments with different biophysical properties.
3 citations
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October 2021 in “Brain Sciences” This review hypothesizes that risperidone long-acting injectable may be linked to bullous pemphigoid in a bipolar patient, though current studies report mixed results.
November 2024 in “Benha Journal of Applied Sciences” In this study, the researchers explored how the loss of structural integrity in hair follicles due to reduced α-SMA expression in the vertex area may contribute to androgenetic alopecia.
December 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study observed that in live rodents, actin filaments adjust their structure to facilitate membrane transfer between cellular compartments; linear filaments stabilize fused membranes, while branched filaments, connected by the protein Ezrin, drive integration, demonstrating actin's role in adapting to membrane biophysical changes.
May 2017 in “Journal of The American Academy of Dermatology” This phase 2 trial found that SM04554, a Wnt signaling modulator, was well-tolerated and increased follicle counts in males with androgenetic alopecia, suggesting potential for promoting hair growth.