TLDR Minoxidil caused a severe rash in a patient, which improved after stopping the drug.
A 54-year-old male with hypertension treated with minoxidil for three years developed a pruritic, erythematous rash that progressed to multiple body areas and impending exfoliation. The rash improved after minoxidil was withdrawn and treated with topical corticosteroids, but reappeared upon accidental rechallenge with the drug. This case highlighted a rare instance of late-onset dermatological toxicity from chronic minoxidil use, suggesting the rash was drug-induced rather than due to other conditions.
15 citations,
October 1981 in “Archives of internal medicine” Minoxidil can cause severe skin reactions like Stevens-Johnson syndrome in rare cases.
35 citations,
July 1981 in “Clinical Pharmacology & Therapeutics” Minoxidil can cause dangerous fluid buildup around the heart.
45 citations,
January 1981 in “Annals of Internal Medicine” Minoxidil controls blood pressure effectively, but may cause side effects like hypertrichosis.
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90 citations,
November 1980 in “Annals of Internal Medicine” Long-term use of minoxidil for high blood pressure can delay kidney failure in some patients and improve kidney function in others with severe hypertension.
51 citations,
October 1980 in “The New England Journal of Medicine” Minoxidil lowers blood pressure effectively but may cause unwanted hair growth and other side effects.
August 2023 in “Journal of Cosmetic Dermatology” Some plants like spinach, broccoli, and matcha may boost the effectiveness of the hair growth drug minoxidil.
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14 citations,
January 2015 in “Skin appendage disorders” Minoxidil treatment for hair loss can cause scalp allergy and severe hair loss.
