20 citations
,
February 1968 in “Journal of Histochemistry & Cytochemistry” This study reports that citrulline, uniquely found in the inner root sheath of hair follicles, can be specifically detected with the carbamido diacetyl reaction, resulting in a bright orange color.
6 citations
,
May 2022 in “Journal of Organometallic Chemistry” This study developed a catalytic system using indenyl-molybdenum(II)-bipyridine complexes and ionic liquid solvents to achieve a 95% yield of campholenic aldehyde from α-pinene oxide under mild conditions.
66 citations
,
January 2008 in “Pharmacology Biochemistry and Behavior” AC-5216 reduces anxiety in mice through neurosteroids affecting GABAA receptors.
34 citations
,
June 2011 in “Alcoholism: Clinical and Experimental Research” This study suggests that neurosteroids and compounds acting on GABA(A) receptors, like THIP, may modulate ethanol intake by influencing drinking patterns.
2 citations
,
December 2008 in “Journal of Chemical Crystallography” This study reports the crystal structure and geometric parameters of a modified Finasteride derivative, highlighting significant differences in dihedral angles compared to its solvated analog and computational models.
March 2008 in “British Journal of Pharmacology” This guide provides an overview of the complex roles and mechanisms of various receptors and channels in pharmacology but does not report new experimental results.
83 citations
,
July 2008 in “Current Opinion in Chemical Biology” This review discusses the structural and functional advances in understanding sulfotransferases and sulfatases, highlighting new insights into enzyme mechanisms and inactivation by clinically relevant aryl sulfamates, but provides no new experimental results.
36 citations
,
July 2017 in “Journal of controlled release” In this study, a new formulation of all-trans retinoic acid bound to polyvinyl alcohol showed reduced skin inflammation and sustained drug release for up to six days compared to free ATRA in vitro and in vivo.
24 citations
,
June 2020 in “Industrial Crops and Products” This study reports that biomass activated carbon fibers derived from metaplexis japonica seed hair effectively adsorb methylene blue dye, demonstrating high capacity and rapid adsorption performance.
October 2023 in “Journal of Molecular Liquids” This study demonstrated that imidazole-based ionic liquids, particularly [Emim]DEP, effectively dissolved yak hair keratin, maintaining its structure better than other tested solvents, and also performed well on human hair and goat wool, with consistent performance even after five recycling cycles.
1 citations
,
November 2021 in “Jurnal Farmasi Indonesia” In this study, three hair tonic formulas containing Kayu Secang extracts demonstrated hair growth activity in rabbits, with the chloroform-methanol fraction showing the most significant results.
12 citations
,
July 2016 in “Journal of dermatology” This study found that intramuscular triamcinolone acetonide may be an effective and safe treatment option for managing refractory alopecia areata, showing a 63% response rate in patients and hair regrowth negatively correlated with initial scalp involvement.
22 citations
,
January 1968 in “THE JOURNAL OF VITAMINOLOGY” This study found that α-tocopheryl acetate is well absorbed through healthy skin, with absorption occurring through specific pathways and showing high affinity for small blood vessels.
134 citations
,
February 2005 in “Neuropsychopharmacology” GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.
305 citations
,
March 2008 in “AJP Endocrinology and Metabolism” This article reviews the regulation and roles of spermidine/spermine-N(1)-acetyltransferase (SSAT) in polyamine metabolism and its potential as a target in cancer and other diseases, without reporting new experimental results.
91 citations
,
July 2004 in “Journal of Biological Chemistry” This study found that overexpression of the enzyme SSAT in a mouse model significantly reduced prostate tumor size and progression, suggesting it could be a promising strategy against prostate cancer.
44 citations
,
October 2019 in “International Journal of Molecular Sciences” This article reviews various studies and suggests that melatonin, produced both naturally in the skin and applied topically, may offer significant protection against environmental damage, making it a promising candidate for skincare therapies.
14 citations
,
January 1995 in “Archives of Physical Medicine and Rehabilitation” This case report describes an individual who developed both localized hypertrichosis and ipsilateral dyshidrotic dermatitis following multiple fractures and cast application, with symptom resolution similar to when these conditions occur independently.
2 citations
,
January 2006 in “PubMed” This study found that topical application of carpronium chloride led to arteriolar vasodilation and increased blood flow in rat mesenteric arterioles, without affecting systemic blood pressure.
1 citations
,
June 2024 in “International Journal of Dermatology” In this study, Alhanshali and co-authors reported that low-dose oral minoxidil, used for treating androgenetic alopecia, may worsen hangover symptoms in some male patients, potentially due to interactions with alcohol that affect blood pressure and metabolic processes.
1 citations
,
January 2016 in “Journal of Headache & Pain Management” This article highlights the need to consider topical minoxidil as a differential diagnosis for unexplained headache and dizziness due to its potential side effects.
January 2026 in “JCEM Case Reports” The researchers reported a case of a 51-year-old woman with primary hypothyroidism who developed anaphylaxis to intravenous levothyroxine after being unresponsive to oral formulations, highlighting potential allergic reactions to IV treatments in such patients.
December 2025 in “JEADV Clinical Practice” This case study reports on a 72-year-old woman with frontal fibrosing alopecia and hair repigmentation, suggesting the rare occurrence of canities reversal could aid in diagnosing FFA.
September 2024 in “Actas Dermo-Sifiliográficas” Sublingual minoxidil is a safe and effective treatment for hair loss, especially in women.
May 2024 in “Archives of dermatological research” This study found that Enz_MoriL, a compound derived from Morus alba L., promotes hair follicle cell proliferation by affecting the Wnt/β-catenin pathway and can counteract an alopecia areata-like condition by suppressing the JAK-STAT signaling in human hair follicle dermal papilla cells.
1 citations
,
June 2015 in “Journal of anatomy” This study reported that novel kainate derivatives, especially ZCZ90, maintained potency in affecting proprioceptive sensory organ firing, aiding future receptor studies for potential treatment innovations.
This study found that 1′S-1′-acetoxychavicol acetate from Alpinia galanga inhibits Nox isozymes and suppresses testosterone-induced hair loss in a mouse model of androgenetic alopecia.
15 citations
,
January 2020 in “RSC advances” In this study, researchers developed a new Supported Ionic Liquid Phase palladium catalyst that showed effectiveness in aminocarbonylation reactions for synthesizing pharmaceutical compounds like CX-546 and a precursor of Finasteride, though results were sensitive to substrate variations and prompted palladium leaching concerns.
1 citations
,
October 2025 in “Iranian journal of pharmaceutical research” This study suggests that geranyl acetate may offer protective, anti-inflammatory, and cytoprotective effects against PPD-induced toxicity in keratinocyte cells, indicating its potential as a plant-derived treatment.
July 2025 in “The Egyptian Journal of Hospital Medicine” This study found that intralesional methotrexate and triamcinolone acetonide have similar efficacy for localized alopecia areata in adults, but differ in safety profiles, with methotrexate associated with hyperpigmentation and triamcinolone with atrophy.