Hairy Drinking May Cause Severe Hangover Symptoms in Patients Taking Low-Dose Minoxidil

The document discusses the potential interaction between low-dose oral minoxidil (LDOM), a common treatment for androgenetic alopecia, and alcohol consumption. Alhanshali and co-authors report that 10 male patients experienced worsened hangover symptoms, such as headaches and nausea, after drinking alcohol while on LDOM. The authors suggest that this may be due to a mild interaction between alcohol and minoxidil, which could lead to additive effects in lowering blood pressure. Additionally, the enzyme sulfotransferase 1A1, involved in minoxidil metabolism, may be affected by ethanol exposure. The study highlights the need for further research into the interactions between alcohol and dermatologic treatments, as well as the broader implications of alcohol on disease pathogenesis and treatment.