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Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.

Using PGPR as biofertilizers can improve soil health and plant growth while reducing reliance on synthetic fertilizers.

Professor Ma Shuanquan treats hair loss by using Chinese medicine to improve liver, spleen, and kidney health.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.

No single treatment is consistently effective for alopecia areata, and more research is needed.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

The peptide IMT-P8 can effectively deliver proteins into the skin and cells for potential skin treatments.

Ruxolitinib can help regrow hair in severe alopecia areata.

Non-obese women with hair loss have higher heart disease risk.

Eat antioxidant-rich foods, reduce fast food, and explore various treatments for vitiligo.

All medications can cause skin rashes, often without a clear cause, and better tests are needed to identify these drug-related skin issues.

Microfluorometry effectively measures how much polymer coats and penetrates hair, useful for evaluating hair products.

UV radiation may cause DNA changes in skin, certain UVB therapy helps psoriasis, a new gene mutation is linked to mild piebaldism, different immune cells affect psoriasis, a drug promotes hair growth, and some cancer drugs could treat skin barrier issues.

Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.

Polysaccharides have many health benefits and are used in drugs, but isolating and purifying them is complex and requires careful methods.

Zinc oxide nanoparticles in sunscreen do not penetrate deep into the skin.

Stress stops hair growth in mice by causing early hair growth phase end and harmful inflammation through a specific nerve-related pathway.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

ICG-enhanced NIR laser therapy may be a promising acne treatment with improvement and no side effects.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

Genetically modified plants could be an important source of omega-3 fats to meet global needs.

Azathioprine's effectiveness and safety require careful monitoring and more research, especially regarding its use with corticosteroids and the role of TPMT status in patients.

PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.

DA liposomes with chloramphenicol effectively target hair follicles and combat MRSA with minimal skin toxicity.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

RADA16 is a promising material for tissue repair and regenerative medicine but needs improvement in strength and cost.