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The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Removing both Atr and Trp53 genes in adult mice causes severe tissue damage and death due to DNA damage.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

Sensitive skin is often caused by nerve fibers and environmental factors, and can be managed with mild skincare and professional advice.

Fatty acid transport protein 4 is essential for skin and hair development.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.

Obesity increases the risk of developing polycystic ovary syndrome, and weight loss can improve the condition.

Women with PCOS have more body fat and thicker fat layers in certain abdominal areas than women without PCOS.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

Type 2 diabetes, bacterial scalp infections, and tight hairstyles like braids and weaves are linked to a higher risk of a scarring hair loss condition in African American women.

The document concludes that specific itchy skin diseases during pregnancy have varying fetal risks and treatments, including corticosteroids and other medications.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

The document concludes that diagnosing and treating Human African Trypanosomiasis is challenging, but new treatments like fexinidazole are promising.

TCDD speeds up skin barrier formation by increasing certain gene expressions.

Mutant mice help researchers understand hair growth and related genetic factors.

The article concludes that better understanding gene regulation related to seasonal changes can offer insights into the mechanisms of seasonal timing in mammals.

The study found that diseases can be grouped by symptoms and that the accuracy of predicting disease-related genes varies with the data source.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.

Memantine may slightly improve memory in people with Down syndrome, but more research is needed.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

Coats' Plus is a genetic disorder with eye abnormalities, brain calcification, poor growth, bone and skin issues, and movement disorders.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.

Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.