20 citations
,
July 2020 in “Expert Opinion on Biological Therapy” This study found that combining micro-needling, low-level laser therapy, and autologous non-activated platelet-rich plasma increased hair density in patients with androgenic alopecia over the treatment period.
20 citations
,
October 2018 in “Aesthetic Plastic Surgery” This review discusses the potential mechanisms of platelet-rich plasma in facial rejuvenation and reports no new clinical results, indicating a theoretical basis for its use in tissue regeneration.
19 citations
,
June 2019 in “Clinical Drug Investigation” This study concluded that platelet-rich plasma injections significantly improved hair density, thickness, and scalp inflammation in both male and female pattern hair loss, with better outcomes in lower-grade cases.
18 citations
,
August 2019 in “Journal of Cosmetic Dermatology” This study found that autologous platelet-rich plasma was associated with increased hair density in people with pattern hair loss, but with considerable variability and unclear risks of bias.
18 citations
,
November 2016 in “Journal of Oral and Maxillofacial Surgery” This review discusses platelet-rich plasma for androgenic alopecia and reports beneficial effects on hair density and quality, but suggests more rigorous studies are needed for conclusive evidence.
16 citations
,
January 2021 in “International Journal of Medical Sciences” This study found that gelatin microspheres loaded with platelet-rich plasma enhanced wound healing in rats by improving inflammatory and angiogenic responses compared to untreated wounds or PRP alone.
16 citations
,
March 2020 in “Facial Plastic Surgery Clinics of North America” The authors concluded that platelet-rich plasma (PRP) shows promising potential as a safe treatment for hair restoration in androgenic alopecia, though further research is needed to refine its use and confirm long-term effects.
15 citations
,
May 2020 in “Journal of Dermatological Treatment” This systematic review and meta-analysis found that platelet-rich plasma treatments improved hair density and thickness in people with androgenetic alopecia, without serious adverse effects.
15 citations
,
April 2020 in “Journal of Dermatological Treatment” This study suggests platelet-rich plasma may be more effective than other non-surgical treatments for male androgenetic alopecia, while low-level laser therapy ranks highest for women; however, the evidence quality was low.
12 citations
,
December 2020 in “Frontiers in Cell and Developmental Biology” This review covers the variability in methods for preparing platelet-rich plasma and reports no new clinical results, suggesting that this variability may contribute to inconsistent efficacy in clinical trials.
12 citations
,
March 2019 in “Journal of Cosmetic Dermatology” This study found that platelet-rich plasma may effectively increase hair follicle numbers in men with androgenetic alopecia, but changes in hair thickness plateaued after the second injection.
12 citations
,
April 2015 in “InTech eBooks” Platelet Rich Plasma (PRP) shows promise for tissue repair and immune response, but more research is needed to fully understand it and optimize its use.
10 citations
,
September 2020 in “Archives of Dermatological Research” Both methods improve hair density and thickness; double-spin may be more effective.
10 citations
,
August 2020 in “Journal of Bioscience and Bioengineering” This study reports that using activated platelet-rich plasma releasate in the preparation of bioengineered hair follicle germs enhanced follicular gene expression and significantly improved hair regeneration in vitro.
10 citations
,
August 2020 in “Dermatologic Therapy” This study found that platelet-rich plasma significantly increased hair diameter in both men and women with androgenetic alopecia but improved hair density only in men.
9 citations
,
July 2020 in “Biomedicine & Pharmacotherapy” This study found that Pep-1-mediated mitochondrial transplantation was as effective as PRP therapy in restoring hair loss related to aging in mice, with distinct improvements in hair and skin-related measures.
9 citations
,
September 2019 in “Journal of Cosmetic Dermatology” This study found that platelet-rich plasma injections significantly increased hair density in men with androgenetic alopecia compared to placebo, but further research is needed to understand factors influencing treatment success.
6 citations
,
March 2021 in “Journal of Cosmetic Dermatology” In this study, platelet-rich plasma treatment improved hair regrowth and characteristics in mice and showed therapeutic efficacy in Chinese patients with androgenetic alopecia.
6 citations
,
February 2020 in “Journal of The European Academy of Dermatology and Venereology” This letter reported that combining platelet-rich plasma with hair transplants did not show benefits for treating androgenetic alopecia.
6 citations
,
October 2018 in “Dermatologic Surgery” This abstract does not present new clinical findings or a research study.
5 citations
,
March 2022 in “Frontiers in Medicine” This review analyzed 17 recent clinical trials on platelet-rich plasma for androgenetic alopecia but reports no new clinical results; the authors seek a consensus on optimal PRP use.
5 citations
,
December 2018 in “Journal of Cosmetic Dermatology” This study found that after treatment with platelet-rich plasma, male androgenetic alopecia patients showed significant improvements in hair count, hair diversity, and reduction in certain dermoscopic features.
5 citations
,
April 2017 in “Dermatologic Surgery” PRP treatment satisfies 58% of female hair loss patients, with most noticing fuller, thicker hair and less shedding.
4 citations
,
September 2020 in “Journal of Cosmetic Dermatology” This study found that platelet-rich plasma injections promote hair growth and are safe and effective for treating androgenetic alopecia.
4 citations
,
December 2019 in “Skin appendage disorders” In this study, manually prepared platelet-rich plasma did not show significant improvement in hair count or anagen hair proportion for men with androgenetic alopecia.
4 citations
,
October 2019 in “Skin appendage disorders” This study found that autologous activated PRP injections significantly increased hair density in patients with androgenetic alopecia, with patients reporting high satisfaction and few side effects.
4 citations
,
January 2015 in “Journal of clinical & experimental dermatology research” This study observed a slight improvement in hair density in men with androgenetic alopecia treated with autologous platelet rich plasma, but only two cases showed cosmetic improvement.
3 citations
,
May 2023 in “Current Molecular Medicine” This review discusses the distinction between platelet-rich plasma and stem cell-based therapies in regenerative medicine, highlighting their different roles and stressing the importance of honest representation by commercial and health entities.
3 citations
,
August 2019 in “Journal of The American Academy of Dermatology” This study found that platelet-rich plasma with microneedling for hair loss was mostly well tolerated, but some patients experienced mild side effects like scalp itching, transient hair shedding, and lymphadenopathy.
3 citations
,
December 2018 in “International Journal of Biomedicine” This study found that treating androgenetic alopecia with platelet rich plasma increased hair density and diameter while decreasing the proportion of telogen and vellus hairs.