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Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Male pattern baldness involves hormones and cell signals affecting hair growth.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

PNU157706 reduced rat sperm movement and fertility without affecting offspring health.

Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

Finasteride boosts morphine's pain relief, stops tolerance, and reduces withdrawal in rats.

A new anti-baldness patch effectively treats hair loss by blocking enzymes linked to the condition.

The activity of a specific rat enzyme in the prostate and epididymis is highly dependent on the acidity level.

Some newly made compounds can block an enzyme linked to hair loss and prostate growth, with one in particular being very selective.

Use "female pattern hair loss" term, assess androgen excess, treat with minoxidil and other medications if needed.

An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.

Finasteride affects prostate weights and pituitary activity differently with age.

5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

Finasteride helps reduce pain and inflammation in animals.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Finasteride exposure harms tadpole reproduction and hormone balance.

The developed model can predict effective 5-alpha-reductase enzyme inhibitors.

Taking oral testosterone with finasteride or dutasteride doubles testosterone levels, and food slightly affects it.

Finasteride may cause slight depression and anxiety.

Finasteride has a higher risk of reproductive side effects than minoxidil.

Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.

Finasteride effectively blocks rat enzymes, but with varying methods and strength.

Iron oxide nanoparticles improve skin penetration and drug release for hair loss treatment.

Post-finasteride syndrome's existence is uncertain; more research needed.

Finasteride worsens seizures in epilepsy rats and speeds up epileptogenesis in mice.