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Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.

Genetic variations affect dutasteride treatment response for male pattern hair loss.

Phototrichogram helps assess hair loss severity.

Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.

Proretinal nanoparticles are a safe and effective way to deliver retinal to the skin.

The right amount of retinoic acid is essential for normal hair growth and development.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

The document concludes that new treatments are needed to better manage acne and reduce side effects related to current therapies.

Vitamin A is important for healthy skin and hair, influencing hair growth and skin healing, but UV light reduces its levels.

Retinoids are effective for various skin conditions and hair loss but have serious side effects, so low doses are recommended.

Modulating Cytochrome P450 activity could help develop new skin disease treatments.

Many popular skincare products claim to prevent aging but lack strong evidence to prove their effectiveness and safety.

9-cis-retinoic acid showed some effectiveness in treating AIDS-related Kaposi sarcoma but had significant side effects at higher doses.

Retinoids can help treat skin pigmentation disorders by affecting melanin production.

Retinoids or their analogs could treat skin pigmentation disorders like melasma and vitiligo.

The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

Thyroid disease can cause hair loss and treating thyroid problems might help with hair disorders.

Oral retinoids are effective for severe skin conditions but require careful use due to side effects.

Stem cells help remove dead cells to keep tissues healthy by balancing cell replacement and clearance.

The document recommends using both clinical evaluation and various measurement methods to assess skin greasiness, considering factors like temperature and hormones.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.

Eating a balanced diet with the right vitamins and minerals is important for healthy hair, but too many supplements can be harmful.

The new micelle formulation delivers acne treatment more effectively and safely than current gels.

Cooling the scalp may prevent hair loss from chemotherapy, hair often grows back after treatment, and nail issues usually improve after stopping the drug.

Newer retinoid drugs are effective for skin conditions but have significant side effects.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.