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The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Genetic variants linked to ten skin diseases were found, showing both immune and non-immune factors play a role.

Telomere damage affects skin and hair follicle stem cells by messing up important growth signals.

KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.

The Wnt signaling pathway is not a major factor in the development of keratoacanthoma, a type of skin tumor.

GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Rare ULBP3 gene changes may raise the risk of Alopecia areata, a certain FAS gene deletion could cause a dysfunctional protein in an immune disorder, and having one copy of a specific genetic deletion is okay, but two copies cause sickle cell disease.

Sdr16c5 and Sdr16c6 genes regulate a key point in lipid production that affects eye and skin gland function.

Creating fully functional artificial skin for chronic wounds is still very challenging.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

Finasteride helps induce ovulation in nonresponder PCOS women.

Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

SCDSFs from zebrafish embryos are beneficial for treating cancer, regenerating tissues, and improving conditions like psoriasis and alopecia.

Nanofiber structure helps regenerate hair follicles.

Dutasteride is more efficient than finasteride, but individual results vary.

The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.

Testosterone and its metabolites have varied effects on different body systems, especially during puberty.

Sheep wool follicles can metabolize both glucose and acetate using different pathways important for wool growth.

Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.

Keratin helps skin cells mature when added to a collagen mix, which could be important for skin and hair health.

Dutasteride, usually used for prostate issues and hair loss, could potentially treat Amyotrophic Lateral Sclerosis (ALS) due to its neuroprotective, antioxidant, and anti-inflammatory properties, but more testing is needed.

Finasteride may affect PNMT, causing side effects.

Diane 35 plus finasteride is more effective in reducing hair growth and androgen levels, but may decrease libido.

Hair gets thinner, grayer, and changes texture with age due to genetics, environment, and cellular changes, affecting the growth cycle.

Athletes need effective management of skin disorders for their performance and well-being.

Increasing mir-302 turns human hair cells into stem cells by changing gene regulation and demethylation.

The symposium highlighted the importance of understanding disease mechanisms for targeted dermatology treatments.