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Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.

Taking 5-alpha reductase inhibitors does not increase the risk of breast cancer in men.

5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.

Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.

5 alpha-reductase inhibitors like finasteride may lower prostate cancer risk and improve cancer screening.

Treatments for hair loss vary, but cell-based options may be the future.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

DHT, a testosterone byproduct, causes male pattern baldness.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.

Two types of 5α-reductase are in dog skin, which might make dutasteride better than finasteride for treating dog hair loss.

Taking Dutasteride with Ketoconazole can increase Dutasteride's effects and side effects.

Finasteride and dutasteride are effective in treating male hair loss but can cause sexual side effects and birth defects.

GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.

The study found that two enzymes linked to hair loss are located in different parts of the scalp, supporting a common treatment's effectiveness.

The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.

PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

Exercise improves insulin sensitivity and hormone regulation in PCOS rats.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

Finasteride effectively treats male pattern hair loss with a 1 mg daily dose.

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.

Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.

The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.

Finasteride effectively treats male hair loss, improving growth and density.

Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.

Dutasteride is more effective than finasteride for hair loss treatment.