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Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.

The document concludes that hair transplantation and gene therapy may be important for future hair loss treatment.

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.

Finasteride's effect on hair loss and prostate enlargement depends on its binding to an enzyme, with maximum impact at 0.2 mg dose.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

The new particle system could be a promising treatment for diseases related to the 5-α reductase enzyme.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

Germacrone from Curcuma aeruginosa may help treat conditions related to male hormones by blocking a specific enzyme.

Allopregnanolone increases growth and changes gene activity in human brain cancer cells.

Female pattern hair loss is common, linked to polycystic ovarian syndrome, and treated with topical Minoxidil.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.

AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.

DHT, a testosterone byproduct, causes male pattern baldness.

Some alternative treatments for hair loss might work, but more research is needed.

Hair diversity is influenced by complex genetics and environmental factors, requiring more research for practical solutions.

Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.

Saw palmetto supplements may modestly improve hair regrowth with few side effects, but more research is needed.

Female pattern hair loss has unclear causes, possibly involving genetics, hormones, and environment, and needs better treatments.

Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.

Effective acne management in PCOS includes hormone therapy, metformin, isotretinoin, weight loss, diet, exercise, and personalized treatment plans.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Dutasteride effectively treats benign prostatic obstruction, improves urinary flow, reduces prostate size, and may prevent prostate cancer, but can cause sexual side effects.

Hair loss drugs may cause sexual issues and infertility in men.

The document concludes that more research is needed to understand hair loss in men and to find new treatments.