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Finasteride blocks progesterone's effect on absence seizures in rats.

Thujae occidentalis semen extract may help treat male pattern baldness by blocking a hair loss-related enzyme and reducing hair loss in mice.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Researchers created a skin patch that delivers two drugs for treating enlarged prostate, which may improve patient use and dosage control.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Dutasteride injections can help hair growth in androgenic alopecia but need more research for long-term use.

Plant-based treatments can effectively and safely treat hair loss.

Activating TSPO helps protect the retina from damage caused by high eye pressure in glaucoma.

Saw palmetto helps with nighttime urination and urine flow, similar to finasteride.

Avicennia marina extract and avicequinone C can potentially promote hair growth and treat hair loss by interfering with hair loss mechanisms and boosting growth factors.

Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Finasteride helps protect brain in old male rats.

Men over 66 taking medication for prostate enlargement have a higher risk of depression and self-harm, especially in the first 18 months of treatment.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.

Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.

Finasteride treats enlarged prostate, improves urinary flow, but may cause sexual side effects.

FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.

Flutamide improves female hair loss when other treatments fail, but may cause liver toxicity.

Four new compounds were more effective than finasteride in treating prostate issues and hair loss, with one being 100 times more active and safe for use.

Ganoderma lucidum may help treat prostate cancer by blocking male hormones and slowing cancer cell growth.

Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.

A new compound effectively inhibits human 5α-reductase 1.

Some treatments like intralesional steroids and 5α-reductase inhibitors are effective for frontal fibrosing alopecia, but more research is needed.

Spironolactone is effective and safe for treating hair loss, excessive hair growth, and acne.

Treatments for hair loss include hormone modifiers, minoxidil, and hair transplant surgery.