6 citations,
October 1993 in “Endocrinology” Finasteride blocks progesterone production in specific tumor cells, potentially causing side effects.
4 citations,
October 2020 in “Toxicology Mechanisms and Methods” Hesperidin protects rat testicles from finasteride damage and improves sperm health.
4 citations,
January 2019 in “Obstetrics & gynecology science” A PET-CT scan successfully located a hard-to-find Leydig cell tumor in a woman with hormonal symptoms.
4 citations,
November 2005 in “The Journal of Urology” Large prostates link to more hair loss.
4 citations,
June 2003 in “Fertility and Sterility” Finasteride doesn't affect ovulation in normal women.
4 citations,
January 2002 in “Indian Journal of Pharmaceutical Sciences” A new method accurately measures finasteride in tablets using color change and light absorption.
3 citations,
April 2010 in “Endocrinology” The mouse model suggests male pattern baldness may be due to an enzyme increasing DHT and higher androgen receptor levels in hair follicles.
2 citations,
July 2018 in “Elsevier eBooks” Some supplements may help with hair loss, but there's not enough strong evidence to recommend them without doctor advice.
2 citations,
March 2012 in “JAMA” Early surgery reduces seizure risk in drug-resistant epilepsy; testosterone to DHT conversion doesn't affect muscle anabolism; veterans with PTSD likely to have riskier opioid use; bevacizumab helps in hereditary bleeding disorder.
2 citations,
February 2004 in “Biopolymers” 4-(4-Phenoxybenzoyl)benzoic acid derivatives can both increase and decrease certain types of reactive oxygen species, and may be relevant to hair loss.
1 citations,
August 2020 in “Food Research” Plant extracts like Avicennia marina, Boehmeria nipononivea, and Camellia sinensis could potentially treat hair loss with fewer side effects than synthetic drugs.
1 citations,
October 2019 in “مجله كليه طب الكندي” Dapsone gel 5% is effective and safe for treating acne.
1 citations,
July 2018 in “Elsevier eBooks” FAPD and possibly CCCA may be AGA subtypes, and treatments combining antiandrogens, hair growth agents, hair transplants, and anti-inflammatories could be effective.
February 2024 in “International journal of biology, pharmacy and allied sciences” Plant-based treatments can effectively and safely treat hair loss.
April 2023 in “Journal of Investigative Dermatology” The research found that certain factors in hair follicle cells control hair growth and development, and these could be used to create new treatments for hair loss.
March 2023 in “Enciclopédia Biosfera” Finasteride effectively treats BPH but requires continuous use to maintain benefits.
January 2016 in “프로그램북(구 초록집)” Hormones and neuropeptides affect hair growth, with androgens having opposite effects on beard and scalp hair.
The document concludes that current treatments for androgenic alopecia are not fully effective, but new therapies like botulinum toxin and PRP show promise, and future gene therapy could be beneficial.
Avicennia marina extract and avicequinone C can potentially promote hair growth and treat hair loss by interfering with hair loss mechanisms and boosting growth factors.
August 2021 in “Skin appendage disorders” Two people lost hair unexpectedly after getting a common hair loss treatment with a drug called Dutasteride.
January 2018 in “Our Dermatology Online” Dutasteride injections can help hair growth in androgenic alopecia but need more research for long-term use.
November 2013 in “Journal of Mazandaran University of Medical Sciences” Minoxidil with caffeine works better for hair loss than minoxidil alone.
March 2005 in “Journal of The American Academy of Dermatology” Two cosmetic lotions improved hair growth and had better cosmetic effects than 2% minoxidil.
August 1993 in “Journal of Dermatological Science” Testosterone metabolism in balding scalp cells may not be the main cause of hair loss.
77 citations,
March 2001 in “Clinics in Dermatology” Androgenetic alopecia involves genetics, hormones, and can be treated with medications or surgery.
5 citations,
July 2022 in “Orphanet journal of rare diseases” RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.
September 2016 in “Journal of Dermatological Science” Wnt-10b is important for keeping mouse skin cells healthy for hair growth.
August 2016 in “Journal of Investigative Dermatology” DHT reduces a cell's ability to promote hair growth, while 3D culture without DHT improves it.
10 citations,
June 2001 in “PubMed” Finasteride is effective in growing hair and stopping hair loss in men with mild to moderate alopecia.
2 citations,
August 2016 in “Experimental Dermatology” Finasteride treats baldness but may cause lasting sexual side effects.