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Men with liver cancer have higher levels of a specific testosterone byproduct in their liver and blood, despite overall lower male hormone levels.

Using 5-alpha-reductase inhibitors, drugs for prostate issues and hair loss, may lead to eye abnormalities in men.

Pueraria mirifica extract may help treat benign prostatic hyperplasia.

Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.

Men over 66 taking medication for prostate enlargement have a higher risk of depression and self-harm, especially in the first 18 months of treatment.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.

Exercise improves insulin sensitivity and hormone regulation in PCOS rats.

Finasteride affects prostate weights and pituitary activity differently with age.

Higher enzyme levels found in women with hair loss, suggesting hormone imbalance.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.

Taking both finasteride and dutasteride for prostate issues may raise the risk of heart problems.

Certain Dibenzo derivatives may help treat prostate cancer.

New drug dutasteride effectively treats hair loss, but use cautiously due to potential sexual side effects.

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

Finasteride effectively inhibits 5α reductase, while plant extracts like Permixon and Bazoton don't show significant results.

Finasteride exposure in pregnancy causes genital abnormalities in male rats.

The study found that two enzymes linked to hair loss are located in different parts of the scalp, supporting a common treatment's effectiveness.

Finasteride effectively reduces hair growth in women with idiopathic hirsutism, but requires careful contraception during treatment.

Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

Finasteride potentially treats hair loss by reducing DHT production.

The medications 5α-reductase inhibitors and spironolactone are generally safe for breast cancer patients on endocrine therapies and do not significantly increase breast cancer risk.

GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.

FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.

Finasteride boosts morphine's pain relief, stops tolerance, and reduces withdrawal in rats.

Finasteride doesn't affect erections much, but may decrease libido in men.

The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.

The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.