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People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.

Finasteride reduces hair loss and treats BPH without major hormone changes, but may cause sexual dysfunction.

Equisetum debile extract, especially the ethyl acetate type, may be a promising natural ingredient for anti-hair loss products.

Finasteride and dutasteride effectively treat hair loss in men and women, but may cause side effects like low libido and depression.

Rice bran extract might help prevent hair loss.

5α-Reductase inhibitors can negatively affect male sexual function and, in some cases, significantly reduce sperm count, but these effects may be reversible.

Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.

5ARI treatment improves hair growth in older men with minimal side effects.

Men with lower education levels are more likely to have erectile dysfunction if they have coronary artery disease.

Dutasteride more effective for hair growth, but has more side effects than finasteride.

Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.

The exact cause of increased 5α-reductase activity leading to hirsutism in women is still unknown.

Dutasteride is more efficient than finasteride, but individual results vary.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

DHT affects testicular development and regulates spermatogenesis in some fish.

Cocaine impairs male sexual behavior and alters testosterone metabolism in the brain.

Testosterone's muscle-building effects do not require its conversion to DHT.

High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.

5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.

Chitosan-coated nanoparticles improve skin delivery of hair loss treatments with fewer side effects.

DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.

Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.

Finasteride effectively lowers specific hormone levels, helping monitor treatment progress.

Taking oral testosterone with or without dutasteride increases testosterone levels and could be an effective treatment for low testosterone.

New tests detect finasteride and dutasteride in urine quickly and easily.

Finasteride doesn't affect antipyrine metabolism, so interactions with cytochrome P-450 enzyme drugs are unlikely.