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Proscar (finasteride) blocks 5α-reductase in sea urchin ovaries and testes, suggesting potential treatment for androgen-related conditions.

Two types of 5α-reductase are in dog skin, which might make dutasteride better than finasteride for treating dog hair loss.

Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.

The study created a new method to test drugs that affect hormone processing in skin.

Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.

Four-amino acid part makes enzyme sensitive to finasteride.

Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

The activity of a specific rat enzyme in the prostate and epididymis is highly dependent on the acidity level.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

New compounds were made that effectively block a specific enzyme related to androgen conditions.

Antidepressants, 5α-reductase inhibitors, and isotretinoin can cause long-lasting sexual dysfunction.

Chitosan-coated nanoparticles improve skin delivery of hair loss treatments with fewer side effects.

The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.

New tests detect finasteride and dutasteride in urine quickly and easily.

The study found that the enzyme linked to acne is present in the same areas of both acne-affected and normal skin.

The study created a model to help design new inhibitors for steroidal 5α-reductase enzymes.

Certain drugs like Dutasteride and Finasteride might help fight SARS-CoV-2 by increasing levels of a steroid called DHEA, which can protect the heart and increase nitric oxide to counteract the virus.

Compounds 4, 4b, and 4c effectively inhibit an enzyme linked to testosterone conversion without significant toxicity.

Dihydrotestosterone and 5α-Reductase play a role in hair loss and prostate health, and finasteride can increase hair growth in men without affecting sperm production, but it doesn't work for postmenopausal women with hair loss.

5α-Reductase inhibitors may increase depression risk but not dementia or suicide.

Scientists found out the structure of a human enzyme linked to prostate cancer and hair loss, which could help in designing drugs.

Dutasteride may protect the brain in early Parkinson's disease.

Neuroactive steroids and the enzyme 5α-reductase might be involved in the development of Tourette's syndrome.

All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.

A reliable model for screening type II 5α-reductase inhibitors was created and validated.

The compounds tested could potentially treat hair loss and alopecia.

New compounds were made that effectively block enzymes related to prostate issues and hair loss.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.