Search
for

    Sort by

    Research 30 of 1000+

    1. The enzyme and inhibitors of 4-ene-3-oxosteroid 5α-oxidoreductase Steroids · 1995 · 64 citations
    2. Wedelolactone, a medicinal plant-derived coumestan, induces caspase-dependent apoptosis in prostate cancer cells via downregulation of PKCε without inhibiting Akt International Journal of Oncology · 2012 · 83 citations
    3. Use of cyproterone acetate (CPA) in the treatment of acne, hirsutism and virilism Journal of Steroid Biochemistry · 1975 · 232 citations
    4. Synthesis and in Vitro Evaluation of 4-Substituted N-(1,1-Dimethylethyl)-3-oxo-4-androstene-17.beta.-carboxamides as 5.alpha.-Reductase Inhibitors and Antiandrogens Journal of Medicinal Chemistry · 1995 · 12 citations
    5. 12 Treatment of hirsutism with 5α-reductase inhibitors Clinics in endocrinology and metabolism · 1986 · 28 citations
    6. Pharmacophore and Atom Based 3D QSAR Studies on the Novel 5-Alpha-Reductase Inhibitors Indian Journal of Pharmaceutical Education · 2018 · 2 citations
    7. An isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of 5-alpha-dihydrotestosterone in human serum and plasma Clinical Chemistry and Laboratory Medicine (CCLM) · 2026
    8. Novel inhibitors of 5α-reductase Expert Opinion on Therapeutic Patents · 2002 · 20 citations
    9. Discovery of Natural Steroid 5 Alpha-Reductase Inhibitors Assay and Drug Development Technologies · 2018 · 11 citations
    10. New 5?-reductase inhibitors: In vitro and in vivo effects Steroids · 2005 · 45 citations
    11. 5α-Metabolism in Finasteride-Treated Subjects and Male Pseudohermaphrodites with Inherited 5α-Reductase Deficiency European Urology · 1991 · 8 citations
    12. Metabolic dysfunction in female mice with disruption of 5α-reductase 1 2017 · 11 citations
    13. Design, synthesis and biological evaluation of novel androst-3,5-diene-3-carboxylic acid derivatives as inhibitors of 5α-reductase type 1 and 2 Steroids · 2017 · 8 citations
    14. Generation of comparative pharmacophoric model for steroidal 5α-reductase I and II inhibitors: A 3D-QSAR study on 6-azasteroids Steroids · 2015 · 13 citations
    15. Evolution, classification, structure, and functional diversification of steroid 5α-reductase family in eukaryotes Heliyon · 2024 · 6 citations
    16. Anti-androgenic activities of the triterpenoids fraction of Ganoderma lucidum Food Chemistry · 2006 · 64 citations
    17. 5α-Reduced glucocorticoids: a story of natural selection Journal of Endocrinology · 2011 · 46 citations
    18. Trends in the Development of New Drugs for Treatment of Benign Prostatic Hyperplasia Current Medicinal Chemistry · 2006 · 14 citations
    19. Side gland of Suncus murinus as a new model of sebaceous gland: 5?-reductase, androgen receptor, and nuclear androgen content in male and female animals Archives of Dermatological Research · 1989 · 7 citations
    20. 17-Oximino-5-androsten-3β-yl esters: synthesis, antiproliferative activity, acute toxicity, and effect on serum androgen level Medicinal Chemistry Research · 2010 · 7 citations
    21. In silico structural prediction of human steroid 5α-reductase type II Medicinal Chemistry Research · 2016 · 3 citations
    22. Caffeic acid N-[3,5-bis(trifluoromethyl)phenyl] amide as a non-steroidal inhibitor for steroid 5α-reductase type 1 using a human keratinocyte cell-based assay and molecular dynamics Scientific Reports · 2022
    23. High-performance liquid chromatographic method for the determination of finasteride in human plasma at therapeutic doses Journal of Chromatography B: Biomedical Sciences and Applications · 1991 · 19 citations
    24. 5α-Reductase Inhibitors, Chemical and Clinical Models Steroids · 1998 · 17 citations
    25. Intracrine androgen biosynthesis, metabolism and action revisited Molecular and Cellular Endocrinology · 2017 · 131 citations
    26. Identification of a Rare Variant in the <i>SRD5A2</i> Gene in Siblings With 46,XY Disorders of Sexual Development Case Reports in Genetics · 2025
    27. Female Hirsutism: Pathophysiological Considerations and Therapeutic Implications* Endocrine reviews · 1984 · 53 citations
    28. Optimization and Transfollicular Delivery of Finasteride-Loaded Proniosomes for Hair Growth Stimulation in C57BL/6Mlac Mice Pharmaceutics · 2021 · 2 citations
    29. AKR1D1 regulates glucocorticoid availability and glucocorticoid receptor activation in human hepatoma cells 2019 · 17 citations
    30. Development and validation of an UPLC method for determination of content uniformity in low-dose solid drugs products using the design space approach Talanta · 2013 · 10 citations