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570-600 / 1000+ resultsresearch Comparative Study Between the Efficacy and Safety of Topical Sildenafil Citrate Solution and Topical Minoxidil 5% in the Treatment of Female Pattern Hair Loss
Topical minoxidil 5% is better for treating female pattern hair loss than topical sildenafil 1%.
research Comparison Between 5% Minoxidil Plus 2% Flutamide Solution vs. 5% Minoxidil Solution in the Treatment of Androgenetic Alopecia
Using both minoxidil and flutamide together is more effective for treating hair loss than using minoxidil alone.
research Comparative Study of the Effect of Topical Minoxidil 5% Versus Combined Fractional CO2 Laser and Topical Minoxidil 5% in the Treatment of Male Androgenetic Alopecia
Combining fractional laser with minoxidil 5% is more effective for treating male hair loss than using minoxidil 5% alone.
research Effectiveness of Topical Minoxidil (5%) Plus Topical Finasteride (0.1%) Fixed-Dose Combination Versus Topical Minoxidil (5%) Plus Oral Finasteride (1 Mg/Day) in Grade II-IV Androgenetic Alopecia: A Randomized, Double-Blind Clinical Trial
research Crystal Structure of Steroid 5-Alpha-Reductase 2 in Complex with Finasteride
research Therapeutic Effects of Growth Factor Cocktail (Cellcurin) Containing FGF5s (Fibroblast Growth Factor 5 Short) and NMN (Nicotinamide Mononucleotide) Applied on the Scalp in Patients with Androgenetic Alopecia: A Split Study
The treatment increased hair growth and thickness in patients with hair loss.
research Effect of Iontophoresis with Growth Factor Cocktail Containing Fibroblast Growth Factor 5-Short Applied to the Scalp in Patients with Androgenetic Alopecia – A Split Study
Iontophoresis with a growth factor cocktail helps hair growth in patients with androgenetic alopecia.
research Therapeutic Effects of Growth Factor Cocktail (CellcurinTM) Containing FGF5s (Fibroblast Growth Factor 5 Short) and NMN (Nicotinamide Mononucleotide) in Patients with Androgenetic Alopecia: A Split Study
The growth factor cocktail significantly increased hair growth in patients with androgenetic alopecia.
research A Randomized Trial of 5% Minoxidil Versus Combination of 5% Minoxidil and Oral Spironolactone in Treatment of Female Pattern Hair Loss
Combining minoxidil and spironolactone is more effective for female hair loss, but minoxidil alone is sufficient after 6 months.
research Comparison of Topical Minoxidil 5% in Ethanol Plus Propylene Glycol Versus Minoxidil 5% in Ethanol Alone in Treatment of Women With Female Pattern Hair Loss
research Dual Effects of 5α-Reductase Inhibitor Dutasteride on Androgenetic Alopecia and Acne Vulgaris
Dutasteride improved both hair loss and acne in two young men.
research Efficacy and Safety of Once-Daily Minoxidil Foam 5% Versus Twice-Daily Minoxidil Solution 2% in Female Pattern Hair Loss: A Phase III, Randomized, Investigator-Blinded Study
Once-daily 5% minoxidil foam increases hair regrowth and density in women with hair loss, but not as effectively as twice-daily 2% minoxidil solution, though it's safer and more convenient.
research Systemic Cyproterone Acetate and 5% Minoxidil Topical in the Treatment of Female Pattern Hair Loss
Systemic cyproterone acetate and 5% topical minoxidil are effective and safe for treating female pattern hair loss.
research Marked Suppression of Dihydrotestosterone in Men with Benign Prostatic Hyperplasia by Dutasteride, a Dual 5α-Reductase Inhibitor
Dutasteride more effectively lowers DHT levels in men with enlarged prostates than finasteride.
research The Clinical Development of a 5α-Reductase Inhibitor, Finasteride
Finasteride effectively treats BPH, but needs more trials to understand potential.
research Dihydrotestosterone and the Concept of 5-Alpha-Reductase Inhibition in Human Benign Prostatic Hyperplasia
Blocking the enzyme that turns testosterone into DHT can safely and effectively treat enlarged prostate.
research Topical Minoxidil Solution (1% and 5%) in the Treatment of Alopecia Areata
Minoxidil solution helps hair regrowth in alopecia areata, with 5% being more effective.
research A Transition State Analogue of 5′-Methylthioadenosine Phosphorylase Induces Apoptosis in Head and Neck Cancers
The study demonstrated that MT-DADMe-ImmA, a potent inhibitor of MTAP, effectively induced apoptosis in head and neck cancer cell lines FaDu and Cal27 by increasing MTA levels and decreasing polyamines, leading to mitochondrial changes and activation of caspases. This treatment selectively targeted cancer cells without affecting normal fibroblasts, suggesting its potential as a cancer treatment. In a mouse model, MT-DADMe-ImmA led to tumor remission, highlighting its promise for cancers sensitive to DNA methylation changes. Despite inducing apoptosis, the treatment did not alter the protein levels of mitochondrial markers Bcl2 and Bax.
research Outcome of Long-Term Treatment with the 5α-Reductase Inhibitor Finasteride in Idiopathic Hirsutism: Clinical and Hormonal Effects During a 1-Year Course of Therapy and 1-Year Follow-Up
Finasteride effectively reduces hair growth in women with idiopathic hirsutism, but requires careful contraception during treatment.
research The Efficacy and Safety of 5α-Reductase Inhibitors in Androgenetic Alopecia: A Network Meta-Analysis and Benefit–Risk Assessment of Finasteride and Dutasteride
Finasteride and dutasteride effectively treat hair loss, but may cause side effects like sexual dysfunction and depression.
research Chronic Telogen Effluvium: A Study of 5 Patients Over 7 Years
Most patients with chronic hair shedding did not progress to permanent hair loss, and one showed improvement with treatment.
research Minoxidil 1 mg Oral Versus Minoxidil 5% Topical Solution for the Treatment of Female-Pattern Hair Loss: A Randomized Clinical Trial
Oral minoxidil and topical minoxidil 5% both effectively improve female-pattern hair loss with safe side effects.
research Comparison of High-Dose Finasteride (5 mg/day) Versus Low-Dose Finasteride (2.5 mg/day) in the Treatment of Hirsutism
Low-dose finasteride effectively treats hirsutism, is safe, and cost-effective.
research Prolonged Treatment with Finasteride (a 5α-Reductase Inhibitor) Does Not Affect Bone Density and Metabolism
Long-term finasteride use doesn't change bone density or metabolism.
research The Extract of Thuja Occidentalis Semen Inhibited 5α-Reductase and Androgenetic Alopecia in B6CBAF1/J Hybrid Mice
Thujae occidentalis semen extract may help treat male pattern baldness by blocking a hair loss-related enzyme and reducing hair loss in mice.
research Biochemical Roles of Testosterone and Epitestosterone to 5α-Reductase as Indicators of Male-Pattern Baldness
High testosterone to epitestosterone ratio in hair could predict male-pattern baldness.
research Diffuse Hypertrichosis During Treatment with 5% Topical Minoxidil
research Doping-Control Analysis of the 5α-Reductase Inhibitor Finasteride: Determination of Its Influence on Urinary Steroid Profiles and Detection of Its Major Urinary Metabolite
Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.
research Decreased Fertility in Male Rats Administered the 5α-Reductase Inhibitor, Finasteride, Due to Deficits in Copulatory Plug Formation
Finasteride reduces male rat fertility by causing issues with copulatory plug formation.