59 citations,
June 2008 in “Journal of The American Academy of Dermatology” The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.
37 citations,
June 2011 in “Journal of Cellular Biochemistry” Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.
31 citations,
March 2018 in “Frontiers in Immunology” The document concludes that anti-dsDNA antibodies are not unique to SLE and their use as indicators is doubtful, highlighting the need for better understanding and classification of the disease.
25 citations,
September 2006 in “Birth Defects Research” Different processes create patterns in skin and things like hair and feathers.
22 citations,
October 2011 in “Bone” Androgens affect bone and fat cell development differently based on the cells' embryonic origin.
14 citations,
June 2021 in “Expert Opinion on Therapeutic Patents” New patents show progress in developing drugs targeting the Wnt pathway for diseases like cancer and hair loss.
14 citations,
October 2000 in “Genomics” Rat dermal papilla cells have unique genes crucial for hair growth.
5 citations,
May 2023 in “Frontiers in immunology” Environmental factors like diet and vitamin levels, especially Vitamin D, can affect autoimmune diseases differently, with lifestyle changes potentially improving outcomes.
May 2024 in “Research Square (Research Square)” PCOS increases sexual pain distress in infertile women.
July 2018 in “British Journal of Dermatology” Mindfulness reduces anxiety and depression in skin disease patients; dermatologists and psychiatrists often lack confidence in treating psychodermatological conditions.
February 2014 in “Medicine - Programa De Formación Médica Continuada Acreditado” The document concludes that non-scarring alopecias can be reversed, but scarring alopecias cause permanent hair loss.
189 citations,
July 2009 in “The Journal of clinical investigation/The journal of clinical investigation” Epidermolysis bullosa simplex causes easily blistered skin due to faulty skin cell proteins, leading to new treatment ideas.
February 2023 in “European biophysics journal” 88 citations,
August 2019 in “Frontiers in immunology” Tyrosine kinases are important in skin autoimmune diseases and could be targets for new treatments.
18 citations,
October 2021 in “Frontiers in Physiology” Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.
15 citations,
January 2021 in “Journal of Materials Chemistry B” Silk nanofiber hydrogels help stem cells heal wounds faster and improve skin regeneration.
1 citations,
January 2022 in “BMC Genomic Data” The study found that androgen receptors in skin cells mainly affect the focal adhesion pathway and control the caveolin-1 gene, with implications for new treatments for related diseases.
214 citations,
April 2017 in “Cell” Different small areas within hair follicles send specific signals that control what type of cells stem cells become.
26 citations,
April 1998 in “Journal of Investigative Dermatology” Sunscreens with higher SPF and UVA filters offer the best protection against skin aging from UVA rays.
1 citations,
March 2024 in “Science” Vitamin A helps skin stem cells decide their function, aiding in hair growth and wound repair.
1 citations,
March 2022 in “IntechOpen eBooks” Collagen is crucial for health and treating certain diseases, and supplements can improve skin, nails, and hair conditions.
39 citations,
February 2011 in “The Prostate/The prostate” Some men's prostate tissues have low enzyme levels due to genetic changes, possibly affecting treatment for prostate enlargement.
23 citations,
May 2019 in “Expert Opinion on Therapeutic Patents” New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.
18 citations,
February 2018 in “International Journal of Molecular Sciences” PGD2 increases androgen receptor activity in hair cells, which could be targeted to treat hair loss.
January 2023 in “Skin appendage disorders” Low-dose oral minoxidil may help treat hair loss but is not FDA-approved and can cause side effects like unwanted hair growth and heart issues.
46 citations,
September 2010 in “Southern Medical Journal” Hair loss treatments include medications and new methods like low-level light therapy, which may work by boosting cell activity and blood flow.
12 citations,
December 2012 in “Current Drug Targets” The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.
50 citations,
April 2010 in “Biology direct” Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.
7 citations,
August 2019 in “Bioorganic & medicinal chemistry” Analog 23 is a promising compound for prostate cancer treatment.
Avicennia marina extract and avicequinone C can potentially promote hair growth and treat hair loss by interfering with hair loss mechanisms and boosting growth factors.