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Finasteride 5mg daily is the most effective for female pattern hair loss, with higher doses of treatments generally more effective.

5-alpha-reductase inhibitors may help stabilize or slow down hair loss in some frontal fibrosing alopecia patients, but more research is needed to confirm their effectiveness and safety.

Using 5 alpha reductase inhibitors may increase dementia risk in the first two years.

Long-term finasteride treatment reduces depression and brain issues in obese male rats.

New nanoparticles deliver plant extracts to hair follicles to treat conditions like hair loss and acne.

Finasteride, when given in high oral doses to pregnant monkeys, caused genital abnormalities in male fetuses, but not in female fetuses or those exposed to intravenous finasteride.

Men on 5-alpha-reductase inhibitors might have worse COVID-19 outcomes.

5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.

Most legal cases about 5α-reductase inhibitors, drugs for hair loss and prostate issues, complain about side effects and delayed cancer diagnosis, with most lawsuits settled out of court.

Plant-based compounds might be effective, low-side-effect treatments for prostate cancer by blocking a specific enzyme.

Dutasteride is more effective than Finasteride in reducing prostate size and PSA levels, but both drugs have similar side effects.

Finasteride improves heart function in obese and aging male rats by reducing oxidative stress and p53 protein levels.

Finasteride harms Daphnia magna's reproduction, growth, and metabolism.

Solanum nigrum may help treat hair loss.

The document concludes that the risk of sexual side effects from 5-alpha-reductase inhibitors is low and often temporary, but more research is needed on potential permanent effects.

5 alpha-reductase inhibitors like finasteride may lower prostate cancer risk and improve cancer screening.

Using 5-alpha-reductase inhibitors, drugs for prostate issues and hair loss, may lead to eye abnormalities in men.

Older patients sticking to their prostate medication saw lasting health benefits.

5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.

DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.

High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.

DHT affects hair follicle cells by changing microRNA levels, leading to less cell growth and more cell death.

Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.

Natural 5AR inhibitors effectively improve mild to moderate hair loss in men.

Plant extracts effectively reduce hair loss and increase growth, offering a safe alternative treatment.

Testosterone undecanoate safely and effectively increased penis size in male children with 5-alpha-reductase deficiency.

Finasteride does not negatively affect male reproductive function.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Hair loss drugs may cause sexual issues and infertility in men.